Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association

    Marcel Proske, Robert Janowski ... Dierk Niessing
    Structural promiscuity in PURA protein, induced by patient mutations, impacts nucleic acid binding, unwinding, and subcellular localization, indicating why so many patients display the full disease spectrum of PURA syndrome.
    1. Cell Biology

    Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

    Mathieu C Husser, Nhat P Pham ... Alisa Piekny
    The split mNeonGreen system enables fast and efficient endogenous tagging in human iPSCs and facilitates the study of proteins in human stem cells and differentiated cells by live imaging.
    1. Cell Biology
    2. Computational and Systems Biology

    De novo-designed minibinders expand the synthetic biology sensing repertoire

    Zara Y. Weinberg, Sarah S. Soliman ... Hana El-Samad
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MEMO1 binds iron and modulates iron homeostasis in cancer cells

    Natalia Dolgova, Eva-Maria E Uhlemann ... Oleg Y Dmitriev
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Heat stress impairs centromere structure and segregation of meiotic chromosomes in Arabidopsis

    Lucie Crhak Khaitova, Pavlina Mikulkova ... Karel Riha
    The sensitivity of Arabidopsis meiotic centromeres to heat stress suggests that centromere function is one of the key determinants of plant reproduction under rising temperatures.
    1. Cell Biology

    High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen

    Wan-ping Yang, Mei-qi Li ... Qian-qian Luo
    Hypobaric hypoxia exposure initiates splenic ferroptosis, reducing red pulp macrophages and exacerbating high-altitude polycythemia by impairing erythrophagocytosis and increasing red blood cell retention.
    1. Cell Biology

    Golgi Apparatus: Making progress

    Jurgen Denecke
    Mapping proteins in and associated with the Golgi apparatus reveals how this cellular compartment emerges in budding yeast and progresses over time.
    Insight
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Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    The Institute of Photonic Sciences, Spain
  3. Richard M White
    Ludwig Institute for Cancer Research, University of Oxford, United Kingdom
  4. See more editors