Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Genetics and Genomics
    2. Immunology and Inflammation

    Transposable elements regulate thymus development and function

    Jean-David Larouche, Céline M Laumont ... Claude Perreault
    Multiomic analyses provide new insights into the involvement of transposable elements in T-cell development in the thymus and central tolerance induction.
    1. Developmental Biology
    2. Genetics and Genomics

    ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse

    Debashish U. Menon, Prabuddha Chakraborty ... Terry Magnuson
    1. Genetics and Genomics

    Explaining the counter-intuitive effectiveness of trophectoderm biopsy for PGT-A using computational modelling

    Benjamin M Skinner, Manuel Viotti ... Peter JI Ellis
    1. Genetics and Genomics

    Defective CAPSL function causes impaired retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy

    Wenjing Liu, Shujin Li ... Xianjun Zhu
    1. Genetics and Genomics
    2. Cancer Biology

    DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers

    Jose Mario Bello Pineda, Robert K. Bradley
    1. Genetics and Genomics

    Deciphering the complex relationship between type 2 diabetes and fracture risk with both genetic and observational evidence

    Pianpian Zhao, Zhifeng Sheng ... Hou-Feng Zheng
    Genetically determined type 2 diabetes (T2D) may not increase the risk of fracture, but managing T2D-related risk factors is crucial to prevent fracture in patients with T2D.
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Spotless: a reproducible pipeline for benchmarking cell type deconvolution in spatial transcriptomics

    Chananchida Sang-aram, Robin Browaeys ... Yvan Saeys
    1. Genetics and Genomics

    The BTB-ZF gene Bm-mamo regulates pigmentation in silkworm caterpillars

    Songyuan Wu, Xiaoling Tong ... Fangyin Dai
    The BTB zinc finger gene Bm-mamo regulates melanin pigmentation in silkworm caterpillars from multiple aspects, including melanin synthesis, pigment granules maturation, and cuticle construction.
    1. Genetics and Genomics
    2. Cancer Biology

    Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

    Rebecca Warfvinge, Linda Geironson Ulfsson ... Göran Karlsson
    1. Genetics and Genomics
    2. Computational and Systems Biology

    Imputation of 3D genome structure by genetic-epigenetic interaction modeling in mice

    Lauren Kuffler, Daniel A. Skelly ... Gregory W. Carter
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Highlights

    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

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    1. Genetics and Genomics
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    1. Genetics and Genomics

    Quantitative Genetics: Explore our collection of articles

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Senior editors

  1. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  2. Murim Choi
    Seoul National University College of Medicine, South Korea
  3. Detlef Weigel
    Max Planck Institute for Developmental Biology, Germany
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