Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Sex-specific behavioral and thalamo-accumbal circuit adaptations after oxycodone abstinence

    Yanaira Alonso-Caraballo, Yan Li ... Elena H Chartoff
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Subregional activity in the dentate gyrus is amplified during elevated cognitive demands

    Charlotte Castillon, Shintaro Otsuka ... Anis Contractor
    Selective engagement of suprapyramidal dentate gyrus neurons during a high-demand pattern separation task reveals blade-specific circuit engagement for enhancing mnemonic discrimination.
    1. Neuroscience

    A meta-analysis suggests that TMS targeting the hippocampal network selectively improves episodic memory

    Elena Badillo Goicoechea, Phillip F Agres ... Joel L Voss
    Meta-analysis indicates that network-targeted non-invasive brain stimulation consistently enhances memory function supported by the hippocampal network, thus providing robust evidence that specific memory abilities rely on specific modifiable brain networks.
    1. Neuroscience

    Effort produces after-effects costly for others but valued for self

    Ya Zheng, Rumeng Tang
    Neural reward signals following effort are amplified for self-benefiting outcomes but attenuated for other-benefiting outcomes, contingent upon reward magnitude and individual effort sensitivity.
    1. Neuroscience

    Brain-wide arousal signals are segregated from movement planning in the superior colliculus

    Richard Johnston, Matthew A Smith
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Locus coeruleus modulation of prefrontal dynamics during attentional switching in mice

    Marco Nigro, Lucas Silva Tortorelli ... Hongdian Yang
    Inhibiting locus coeruleus input to the medial prefrontal cortex in mice impaired task performance, affected the tuning of single cortical neurons and disrupted population dynamics and encoding capacity during attentional switching.
    1. Immunology and Inflammation
    2. Neuroscience

    Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability

    Simone Carneiro-Nascimento, Chao Wei ... Dan Levy
    Intravital microscopy of meningeal macrophage Ca²⁺ dynamics reveals previously unknown population heterogeneity, vasomotion-coupled activity, and diverse responses during steady state and neuroinflammatory conditions, offering relevant insights into brain immune regulation.
    1. Neuroscience

    A context-free model of savings in motor learning

    Mahdiyar Shahbazi, Olivier Codol ... Paul L Gribble
    Recurrent neural network models trained on a novel motor skill exhibit a persistent shift in preparatory activity that enables faster relearning, without cognitive or contextual cues.
    1. Neuroscience

    Characterisation of cold-selective lamina I spinal projection neurons in the mouse

    Aimi N Razlan, Wenhui Ma ... Junichi Hachisuka
    Lamina I projection neurons that respond selectively to skin cooling receive monosynaptic input from Trpm8-expressing primary afferents and innervate brain regions involved in perception of cold and cold defence mechanisms.
    1. Neuroscience

    Modeling flexible behavior with remapping-based hippocampal sequence learning

    Yoshiki Ito, Taro Toyoizumi
    A biologically plausible reinforcement learning model that integrates associative memory and hippocampal remapping explains context-dependent flexible behavior, neural dynamics, and psychosis-related symptoms.

Highlights

    1. Cell Biology
    2. Neuroscience

    The role of lipids in hearing

    Yein Christina Park, Angela Ballesteros
    1. Neuroscience

    Cilia reveal their secrets

    Ruth Anne Eatock, Marina Kabirova
    1. Neuroscience

    The sound of neural silence

    Nikki Tjahjono, Yu-Shun Wang, Lin Tian

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Tirin Moore
    Howard Hughes Medical Institute, Stanford University, United States
  3. Jonathan Roiser
    University College London, United Kingdom
  4. See more editors