Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Neuroscience

    Ptbp1 is not required for retinal neurogenesis and cell fate specification

    Haley Appel, Rogger P Carmen-Orozco ... Seth Blackshaw
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Traveling waves across scales: Different mechanisms but same canonical computation?

    Laura Dugué, Frédéric Chavane
    The review proposes a novel mechanistic distinction between first- and second-order traveling waves that subserves a same canonical computation by ordering neuronal processing to impose a computational syntax.
    1. Neuroscience

    A deep learning approach for the analysis of birdsong

    Therese MI Koch, Ethan S Marks, Todd F Roberts
    An open-source deep learning toolkit performs accurate annotation and similarity scoring of zebra finch song, along with comprehensive feature extraction, enabling consistent, interpretable comparisons of vocal phenotypes across research groups.
    1. Developmental Biology
    2. Neuroscience

    Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function

    Caleb CS Calhoun, Mary ES Capps ... Summer B Thyme
    Sensitive brain activity mapping and behavioral profiling reveal most microexons are dispensable for early brain development but highlight a small subset with intriguing neural phenotypes for future study.
    Version of Record
    Short Report
    • Important
    • Solid
    1. Neuroscience

    Mother-child dyadic interactions shape the developing social brain and Theory of Mind in young children

    Lei Li, Jinming Xiao ... Xujun Duan
    Children’s social cognitive development emerges from the dynamic interplay of neural maturation, parental caregiving, and dyadic brain-to-brain synchrony.
    1. Neuroscience

    Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem

    Zahra Khodadadi, Daniel Trpevski ... Jeanette Hellgren Kotaleski
    Biophysically detailed modeling predicts that a biologically plausible synaptic plasticity rule, gated by calcium and dopamine, enables single neurons to solve nonlinear binding tasks by exploiting dendritic nonlinearities.
    1. Neuroscience

    Prefoldin 5 is a microtubule-associated protein that suppresses Tau-aggregation and neurotoxicity

    Anjali Bisht, Srikanth Pippadpally ... Vimlesh Kumar
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    CO2-dependent opening of Connexin 43 hemichannels

    Valentin-Mihai Dospinescu, Alexander Mascarenhas ... Nicholas Dale
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Elevated DNA damage without signs of aging in the short-sleeping Mexican cavefish

    Evan Lloyd, Fanning Xia ... Alex C Keene
    Cavefish exhibit resilience to chronic sleep loss and tolerate elevated DNA damage and reduced DNA repair responses without compromising healthspan or longevity.
    1. Neuroscience

    Relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis

    Yue Wang, Richard Anney, Narun Pat
    Multimodal neuroimaging explained 66% of the cognitive–mental health link in children, outperforming polygenic scores (21%), and accounted for 58% of the environmental contribution to this relationship.

Highlights

    1. Neuroscience

    Hunger and neuronal migration

    Fang-Shin Nian, Laurent Nguyen
    1. Neuroscience

    The power of chemogenetics

    Maria Puchik, Igor Kagan
    1. Genetics and Genomics
    2. Neuroscience

    How stress can extend lifespan

    Loren Cocciolone, Valeria Uvarova, Patricija van Oosten-Hawle

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Yanchao Bi
    Peking University, China
  3. Michael J Frank
    Brown University, United States
  4. See more editors