A Research Advance is a short article that allows either the authors of an eLife paper or other researchers to publish new results that build on the original research paper in an important way.
Mathieu Hénault, Souhir Marsit ... Christian R Landry
The gain of transposable elements in yeast hybrids does not scale with genetic divergence levels and is most impacted by structural variations and multiple aspects of individual hybrid genetic backgrounds.
Rachel A Johnston, Katherine A Aracena ... Jenny Tung
A massively parallel reporter assay, mSTARR-seq, reveals widespread DNA methylation-environment interactions across the genome, prioritizing CpG sites identified in epigenome-wide association studies that may be most relevant to biological embedding.
Region of Attainable Redaction analysis allows scientists to estimate the potential impacts of redaction in biomedical science, helping to uncover potentially spurious or non-robust results.
Diek W Wheeler, Jeffrey D Kopsick ... Giorgio A Ascoli
Hippocampome.org v1.0, a foundational classification system of hippocampal neuron types, has evolved into 2.0, which recenters the focus on new functionality to build real-scale, biologically detailed, data-driven computational simulations.
Romina Piscitello-Gómez, Franz S Gruber ... Suzanne Eaton
Quantitative analysis of cell dynamics over a range of timescales reveals that core PCP is not required to organize large-scale tissue flows but does affect short timescale mechanics.
Clare Andradi-Brown, Jan Stephan Wichers-Misterek ... Anna Bachmann
An enhanced bioinformatic pipeline to quantify Plasmodium falciparum core gene and polymorphic var gene expression revealed changes occurring during early culture adaptation of parasites from naturally infected individuals.
Numerous pathways/function predictions were identified via gene sets, phosphopeptides, and phosphoproteins, which may point to potential novel therapeutic targets to enhance heart adaptivity, maintaining heart performance while avoiding cardiac dysfunction.