Figure 1. | Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

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Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

Figure 1.

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University of California, San Francisco, United States; University of Pennsylvania, United States
Figure 1.
Download figureOpen in new tabFigure 1. Illustrations of the genealogies of different replication modes.

Red dots indicate positive-sense strands. Blue dots indicate negative-sense templates. Stamping machine (SM) progeny are one generation from the initial infecting genome (left). In an example of geometric replication (GR), progeny are an average of 2.33 generations from the initial infecting genome (right).

DOI: http://dx.doi.org/10.7554/eLife.03753.003