Figure 1—figure supplement 2. | Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish

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Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish

Figure 1—figure supplement 2.

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California Institute of Technology, United States
Figure 1—figure supplement 2.
Download figureOpen in new tabFigure 1—figure supplement 2. Clonidine treated larvae are less active and sleep more than vehicle treated controls during the day.

Representative activity (A), waking activity (B) and sleep (C) traces of vehicle (blue) and clonidine (red) treated zebrafish larvae. Bar graphs of activity (D), waking activity (E), sleep (F), sleep bout number (G), sleep bout length (H) and sleep latency (I) from two combined experiments (n > 140 for each condition). Bars represent mean ± s.e.m. *, p < 0.05; **; p < 0.001; ***, p < 0.0001 by one-way ANOVA.

DOI: http://dx.doi.org/10.7554/eLife.07000.005