Figure 1—figure supplement 3. | Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish

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Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish

Figure 1—figure supplement 3.

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California Institute of Technology, United States
Figure 1—figure supplement 3.
Download figureOpen in new tabFigure 1—figure supplement 3. Bopindolol treated larvae sleep more than vehicle treated controls.

Representative activity (A), waking activity (B) and sleep (C) traces of vehicle (blue) and bopindolol (red) treated zebrafish larvae. Bar graphs of activity (D), waking activity (E), sleep (F), sleep bout number (G), sleep bout length (H) and sleep latency (I) from two combined experiments (n > 140 for each condition). Bars represent mean ± s.e.m. n indicates number of larvae. *, p < 0.05; **, p < 0.001; ***, p < 0.0001 by one-way ANOVA.

DOI: http://dx.doi.org/10.7554/eLife.07000.006