Figure 1. | Cell-to-cell infection by HIV contributes over half of virus infection

Open accessCopyright infoDownload PDFDownload figures

Cell-to-cell infection by HIV contributes over half of virus infection

Figure 1.

Affiliation details

Kyushu University, Japan; Japan Science and Technology Agency, Japan; Kyoto University, Japan; University of Tokyo, Japan; Hospital Saint Louis, France; Université Paris Diderot, Sorbonne Paris Cité, France; Tokyo University of Agriculture, Japan
Figure 1.
Download figureOpen in new tabFigure 1. Cell culture systems and the basic reproduction number under cell-to-cell and cell-free infection.

(A) Static and shaking cultures of Jurkat cells. The static and shaking cell cultures allow human immunodeficiency virus type 1 (HIV-1) to perform both cell-free and cell-to-cell infection, and only cell-free infection, respectively. (B) The basic reproduction number, R0, is defined as the number of the secondly infected cells produced from a typical infected cell during its infectious period. In the presence of the cell-to-cell and cell-free infection, the basic reproduction number consists of two sub-reproduction numbers through the cell-free infection, Rcf, and through the cell-to-cell infection, Rcc, respectively.

DOI: http://dx.doi.org/10.7554/eLife.08150.003