Figure 4—figure supplement 1. | Modulation of anxiety and fear via distinct intrahippocampal circuits

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Modulation of anxiety and fear via distinct intrahippocampal circuits

Figure 4—figure supplement 1.

Affiliation details

McLean Hospital, United States; Harvard Medical School, United States; The University of Tennessee Health Science Center, United States; Yale School of Medicine, United States; Russian Academy of Sciences, Russia; University of Zurich, Switzerland
Figure 4—figure supplement 1.
Download figureOpen in new tabFigure 4—figure supplement 1. Frequency and power of theta range oscillations.

A-D Mean ( ± S.E.M.) peak frequency in the theta range in dHPC recorded before, 30min after and 60min after diazepam administration in (A) α2F/F, (B) α2CA1KO, (C) α2CA3KO, (D) α2DGKO mice.**p<0.01, ***p<0.001 compared to pre-diazepam baseline at the given stimulating current. (E) Mean ( ± S.E.M.) change from baseline slope in the stimulation intensity – peak frequency function for dHPC recordings 30 min (left) or 60 min following diazepam injection,*p<0.05 compared to corresponding α2F/F group. (F) Mean ( ± S.E.M.) theta power in the vHPC normalized to baseline power 60 min following diazepam injection. (G) Same as F for dHPC recordings. *p<0.05 compared to corresponding α2F/F group.

DOI: http://dx.doi.org/10.7554/eLife.14120.020