Figure 5. | Uncertainty leads to persistent effects on reach representations in dorsal premotor cortex

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Uncertainty leads to persistent effects on reach representations in dorsal premotor cortex

Figure 5.

Affiliation details

McCormick School of Engineering, Northwestern University, United States; Feinberg School of Medicine, Northwestern University, United States; Northwestern University, United States
Figure 5.
Download figureOpen in new tabFigure 5. Tuning-related changes in activity with uncertainty.

(A) Spatiotemporal activity maps for PMd and M1. Neurons were binned on each trial by the distance between their preferred directions and the reach direction. Color indicates average change in firing rate from baseline in spikes per second. Left and right plots in each panel are aligned to target onset (T) and reach onset (R) respectively. (B) Average change from baseline for SD and OD neurons in the initial center-out block (zero uncertainty; top) and subsequent blocks with low (bue) and high (red) uncertainty targets (bottom). High uncertainty trials resulted in reduced early activity for both SD and OD neurons in PMd, but an increase in OD activity for the remainder of the delay and movement phases. ORTH neurons were omitted for visibility. Error bars represent bootstrapped 95% confidence bounds on the mean estimate. For all plots, PDs were calculated separately for visual, delay, and movement epochs.

DOI: http://dx.doi.org/10.7554/eLife.14316.008