Figure 9. | Uncertainty leads to persistent effects on reach representations in dorsal premotor cortex

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Uncertainty leads to persistent effects on reach representations in dorsal premotor cortex

Figure 9.

Affiliation details

McCormick School of Engineering, Northwestern University, United States; Feinberg School of Medicine, Northwestern University, United States; Northwestern University, United States
Figure 9.
Download figureOpen in new tabFigure 9. Differences in PMd activity correlate with differences in behavioral uncertainty rather than differences in the weighting of the visual cue.

(A) Eighteen sessions (filled symbols) selected for monkey M in order to increase the correlation between ∆behavioral uncertainty and ∆cue weighting (top). Across these select sessions both metrics could explain the observed differences in OD activity (bottom). (B) Alternate subsampling that minimized the correlation between the two behavioral metrics (top). This resampling did not change the correlation between changes in OD activity and ∆behavioral uncertainty (lower left). However, it eliminated the correlation between ∆cue weighting and OD activity (lower right). (C) Correlations of OD differences with ∆behavioral uncertainty (filled) and ∆cue weighting (open) for 1000 unique 18-session subsamples. Each is plotted against the correlation between ∆behavioral uncertainty and ∆cue weighting. The correlation with ∆behavioral uncertainty was consistently stronger than with ∆cue weighting. The correlation with ∆cue weighting was only strong when ∆cue weighting and ∆behavioral uncertainty were well correlated with each other. (D) Same as in C, but for monkey T. Each subsample contains six trial blocks. Unlike monkey M, ∆cue weighting and ∆behavioral uncertainty were negatively correlated across sessions. Regardless, OD activity in PMd was still positively correlated with ∆behavioral uncertainty.

DOI: http://dx.doi.org/10.7554/eLife.14316.013