Figure 3—figure supplement 1. | Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels

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Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels

Figure 3—figure supplement 1.

Affiliation details

Harvard University, United States; Howard Hughes Medical Institute, Harvard University, United States
Figure 3—figure supplement 1.
Download figureOpen in new tabFigure 3—figure supplement 1. Use-dependent inhibition of NaV1.7 by amitriptyline and TTX.

Data used to produce Figures 3C,D. Plots show the fluorescence response evoked by the test pulse with variable duration prepulses. Each trace is the average of n = 3–5 wells for amitriptyline or n = 4–6 wells for TTX.

DOI: http://dx.doi.org/10.7554/eLife.15202.010