Figure 5. | Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

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Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

Figure 5.

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City College of the City University of New York, United States; New York University School of Medicine, United States; Mayo Clinic, United States
Figure 5.
Download figureOpen in new tabFigure 5. Voltage and electric field for measurements and model.

All values are calibrated to 1 mA stimulation. (A) False-color representation of measured voltages for patient P03. (B) Voltages from the corresponding individualized model across the cortical surface. (C) Absolute voltage difference between recording and model predictions. (D) Comparison of recorded voltages with values predicted by the individualized model for P03. Each point in the scatter plot represents an intracranial electrode as shown in (A), with black indicating cortical surface electrodes and red representing depth electrodes (mostly targeting hippocampus). (E) Projected electric field is measured in the direction of nearby electrodes (pairs connected by blue lines in (D)), and is calculated as the voltage difference divided by the distance between the two electrodes. Error bar at each point indicates the standard variation of the measured electric field at the corresponding electrode as shown in Figure 3C). (F) Projected electric field for cortical surface recordings and corresponding model predictions combining all the subjects. (G) Same as (F) showing all the depth electrodes.

DOI: http://dx.doi.org/10.7554/eLife.18834.006

Figure 5—source data 1.Animated 3D renderings of the recorded and model-predicted voltages for each subject, and the absolute difference between the two.

The predicted values are from the individually optimized models.

DOI: http://dx.doi.org/10.7554/eLife.18834.007

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