Figure 1—figure supplement 5. | TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

Open accessCopyright infoDownload PDFDownload figuresRelated content

TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

Figure 1—figure supplement 5.

Affiliation details

Cold Spring Harbor Laboratory, United States; Stony Brook University, United States; Huntington Hospital, Northwell Health, United States; University of Southern California, United States; Cancer Research UK – Cambridge Institute, University of Cambridge, United Kingdom
Figure 1—figure supplement 5.
Download figureOpen in new tabFigure 1—figure supplement 5. Quantification of apoptosis-mediated increase in lethality in H1650-M3 and H1650.

The chart depicts quantification of relative amounts of Cleaved-caspase-3 between H1650-M3 and H1650 from the immunoblots indicated in Figure 1F. Levels of intensity of each band were quantified using imajeJ32 software and is represented as a ratio to Pro-Caspase-3. The data represent mean ± SD from two independent experiments. p-value *<0.05, **<0.005, unpaired t-test.

DOI: http://dx.doi.org/10.7554/eLife.21615.008