Figure 4—figure supplement 2. | TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

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TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

Figure 4—figure supplement 2.

Affiliation details

Cold Spring Harbor Laboratory, United States; Stony Brook University, United States; Huntington Hospital, Northwell Health, United States; University of Southern California, United States; Cancer Research UK – Cambridge Institute, University of Cambridge, United Kingdom
Figure 4—figure supplement 2.
Download figureOpen in new tabFigure 4—figure supplement 2. TGF-β reduces the efficiency of homologous recombination in a DR-GFP assay in H1650 cells.

The chart represents the percentage of GFP-positive cells upon transfection with pDR-GFP or pCBASce-I or both, under vehicle or TGF-β treatment. Each bar represents mean ± SD of three replicates from two independent experiments. (p-value **<0.005, unpaired t-test with desired FDR 1%.)

DOI: http://dx.doi.org/10.7554/eLife.21615.024