Figure 7—figure supplement 1. | TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

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TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

Figure 7—figure supplement 1.

Affiliation details

Cold Spring Harbor Laboratory, United States; Stony Brook University, United States; Huntington Hospital, Northwell Health, United States; University of Southern California, United States; Cancer Research UK – Cambridge Institute, University of Cambridge, United Kingdom
Figure 7—figure supplement 1.
Download figureOpen in new tabFigure 7—figure supplement 1. A549 cells undergo changes in the surface expression of CD44 and CD24 before, during and after exposure to TGF-β.

The chart depicts the percentage of of A549 cells in the CD44+/CD24− state and the CD44−/ CD24+ state, before, during and post exposure to TGF-β. A549 cells before, during and post exposure to TGF-β were stained for surface expression of CD44 and CD24 and analyzed by FACS. Each bar represents the mean ± SD of three replicates from three independent experiments. 10,000 cells were analyzed for each replicate of each sample.

DOI: http://dx.doi.org/10.7554/eLife.21615.030