The 243 words that appeared in at least one million PubMed records as of July 28, 2018. The words are ranked by number of appearances (second column). the 139211417 of 112854806 and 84215510 in 70197546 to 47013634 a 41370842 with 30246472 was 24206336 for 22600525 were 21471088 that 18280936 is 18227406 by 17271385 as 12016804 on 12011786 patients 11772152 from 11384398 this 11080346 or 10218358 are 9712259 at 9561066 be 9237307 an 9120830 we 7971299 these 7021680 not 6852516 cells 6522511 study 5647890 which 5448562 have 5437508 after 5374766 than 5300838 between 5091970 but 4331569 been 4260206 treatment 4198501 results 4185004 has 4101120 both 4062938 it 4010595 cell 3973786 may 3967672 two 3936405 using 3926556 group 3886116 also 3768744 had 3746995 during 3673771 p 3642899 all 3630831 no 3610491 their 3529102 more 3502410 used 3370307 activity 3290340 can 3259258 increased 3077182 protein 3024529 data 2976588 levels 2963447 other 2959613 found 2935639 significantly 2924095 one 2922048 disease 2865062 compared 2830223 significant 2827122 expression 2800756 clinical 2766556 analysis 2749713 effect 2630638 associated 2596587 effects 2574152 showed 2569343 there 2567762 different 2533871 when 2520858 studies 2517174 only 2503235 its 2465530 high 2449757 however 2415170 control 2409254 into 2333829 human 2330337 most 2320956 years 2317051 observed 2262764 time 2251421 cases 2223890 use 2139026 our 2130563 higher 2111852 blood 2097518 three 2095536 gene 2086885 groups 2070575 rate 2058700 such 2057454 age 2056815 risk 2027796 response 2015487 present 2015185 cancer 1988391 those 1986315 who 1900390 increase 1897366 well 1895506 system 1885422 changes 1838271 normal 1805545 respectively 1797362 patient 1793817 first 1784158 model 1773740 mean 1760305 role 1756578 acid 1722207 factors 1695355 total 1693498 lt 1672831 function 1668194 method 1663526 among 1631804 less 1620337 new 1620330 health 1618167 within 1617889 could 1612097 number 1601898 each 1596390 level 1595269 did 1582759 therapy 1581414 development 1570824 performed 1570596 low 1561433 growth 1556000 suggest 1538257 important 1520166 mice 1502261 type 1499730 days 1494287 dna 1492973 c 1487168 rats 1481174 similar 1459274 lower 1444203 while 1442701 they 1442228 some 1434626 without 1432893 presence 1431229 children 1424913 months 1418450 women 1408717 specific 1384677 proteins 1377592 potential 1364948 through 1362519 obtained 1360884 studied 1359836 tumor 1358059 serum 1355450 tissue 1353872 reported 1352687 over 1347688 binding 1329663 including 1328077 subjects 1327074 reduced 1326587 n 1314948 factor 1314489 concentrations 1313250 based 1310910 plasma 1309973 findings 1308349 identified 1293750 receptor 1292837 differences 1285132 care 1282476 although 1281871 treated 1281029 decreased 1275425 test 1271496 measured 1266414 about 1243132 addition 1223951 under 1216766 further 1215473 primary 1212694 early 1209869 concentration 1209194 due 1203742 case 1188526 h 1185805 diagnosis 1182783 following 1182221 genes 1181656 infection 1173398 conditions 1170146 b 1169537 show 1168019 period 1151375 should 1149338 related 1147987 either 1145130 induced 1140860 examined 1136616 four 1135782 evidence 1132120 investigated 1126739 positive 1126392 developed 1125151 range 1118986 demonstrated 1115545 determined 1113135 revealed 1112304 several 1110977 activation 1098957 samples 1078910 liver 1071566 surgery 1069711 same 1065857 major 1065607 before 1056801 values 1052409 greater 1043618 survival 1037913 species 1037851 shown 1034245 acute 1032722 per 1031331 determine 1030907 brain 1030730 population 1025505 t 1024468 complex 1021814 pressure 1021473 bone 1016619 whereas 1010808 vitro 1006285 drug 1005902