Nonlinear H₂O₂ scavenging by peroxiredoxins drives acquired stress resistance and replicative lifespan hormesis.

Mutations in several components of a bacterial ribosome are shown to broadly decrease antibiotic and stress sensitivity, and readily accessible reversion mutations allow these ribosomal mutations to serve as stepping stones to high level antibiotic resistance.

IRE-1 manipulates tumor cell identity to restore apoptosis sensitivity and suppress an aggressive germline tumor in C. elegans.

A biomechanical approach inducing confined cell migration reveals that mechanical stress has a profound effect on cancer cell survival.

Helitron transposable elements, by providing high density transcription factor binding sites upstream of host genes, have diversified the heat shock response within and among Caenorhabditis species.

Erlotinib-resistant AXL overexpressing cells are present in therapy-naive tumors, and expression of AXL in these cells is regulated through a stochastic mechanism centered on the epigenetic regulation of miR-335.

Unique integrate stress response sensors differentially trigger pro-survival versus pro-apoptotic responses in cells confronted with Hsp70 inhibitor-associated proteotoxic challenges.

Bacteria growing in biofilms evolve antimicrobial resistance via different pathways and generate greater genetic diversity than well-mixed populations, selecting fitter but less resistant genotypes.

Malaria remodels the spleen to imprint tolerance and reduce pathology in subsequent infections.

When the fear-enhancing effects of prior exposure to stress are absent, the expression of fear reflects normal neural activity in the medial prefrontal cortex, not stress-induced hyperactivity in the amygdala.