8,779 results found
    1. Neuroscience

    Sexually divergent expression of active and passive conditioned fear responses in rats

    Tina M Gruene, Katelyn Flick ... Rebecca M Shansky
    Female, but not male rats exhibit an active conditioned fear response, which challenges traditional approaches to measuring fear learning exclusively through freezing, and suggests that females use a more diverse set of threat strategies.
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    1. Neuroscience

    Spatial modulation of visual responses arises in cortex with active navigation

    E Mika Diamanti, Charu Bai Reddy ... Matteo Carandini
    Spatial modulation along the visual pathway arises in the cortex and strengthens with active navigation and experience.
    1. Neuroscience

    C1 neurons are part of the circuitry that recruits active expiration in response to the activation of peripheral chemoreceptors

    Milene R Malheiros-Lima, Josiane N Silva ... Thiago S Moreira
    An unbiased description reveals potential implications for understanding the developmental mechanisms that match respiratory supply and demand during hypoxia.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    KRAB-zinc finger protein gene expansion in response to active retrotransposons in the murine lineage

    Gernot Wolf, Alberto de Iaco ... Todd S Macfarlan
    Unbiased ChIP-seq screens and genetic knockouts of large Kruppel associated box zinc finger protein (KRAB-ZFP) clusters reveal that evolutionarily young KRAB-ZFPs play a redundant role in retrotransposon restriction in mice.
    1. Neuroscience

    A limbic circuit selectively links active escape to food suppression

    Estefania P Azevedo, Bowen Tan ... Sarah A Stern
    Lateral septum neurotensin neurons are active in response to stress where escape is a viable strategy and decrease consumption via effects on hypothalamic pathways regulating food intake.
    1. Neuroscience

    Predominantly linear summation of metabotropic postsynaptic potentials follows coactivation of neurogliaform interneurons

    Attila Ozsvár, Gergely Komlósi ... Gábor Tamás
    Summation of metabotropic GABAergic responses remain linear even if most superficial layer interneurons specialized to recruit GABAB receptors are simultaneously active.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic

    Aaron S Mendez, Jennifer Alfaro ... Peter Walter
    A rationally designed small molecule ATP-mimetic activates IRE1 and PERK signaling in cells by inducing conformational changes that template the assembly of higher-order enzymatically active structures.
    1. Cell Biology
    2. Physics of Living Systems

    Force propagation between epithelial cells depends on active coupling and mechano-structural polarization

    Artur Ruppel, Dennis Wörthmüller ... Martial Balland
    Combining micropatterning, traction force microscopy, and optogenetics, it is shown that epithelial cells actively respond to mechanical signals from neighboring cells.
    1. Neuroscience

    A unified internal model theory to resolve the paradox of active versus passive self-motion sensation

    Jean Laurens, Dora E Angelaki
    Central vestibular regions in the brainstem and cerebellum perform dynamic Bayesian inference to combine motor commands and sensory signals into an optimal estimate of self-motion.
    1. Physics of Living Systems

    Dynamic density shaping of photokinetic E. coli

    Giacomo Frangipane, Dario Dell'Arciprete ... Roberto Di Leonardo
    The concentration of motile bacteria, expressing a light-driven proton pump, can be precisely controlled in space and time by spatially modulating their swimming speeds with a structured light pattern.

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