7,045 results found
    1. Neuroscience

    Human subthalamic nucleus activity during non-motor decision making

    Baltazar A Zavala, Anthony I Jang, Kareem A Zaghloul
    Intraoperative human brain recordings during a memory task reveal that when participants inhibit memory formation, the subthalamic nucleus shows higher beta power and beta coherence with areas of the lateral cortex implicated in memory processing.
    1. Neuroscience

    A robust activity marking system for exploring active neuronal ensembles

    Andreas T Sørensen, Yonatan A Cooper ... Yingxi Lin
    A new system for tagging activated neuronal population offers multiple advantages over existing systems based on immediate early genes, including greater sensitivity and specificity, and suitability for easy application in species other than mice.
    1. Neuroscience

    Subthalamic nucleus gamma activity increases not only during movement but also during movement inhibition

    Petra Fischer, Alek Pogosyan ... Huiling Tan
    Sudden stopping of rhythmic movement is associated with a pronounced increase of 60-90 Hz gamma oscillations in the subthalamic nucleus, which have formerly been regarded as favouring movement.
    1. Neuroscience

    Cerebellum encodes and influences the initiation, performance, and termination of discontinuous movements in mice

    Michael A Gaffield, Britton A Sauerbrei, Jason M Christie
    The activity of cerebellar Purkinje cells both represents and participates in organizing the temporal structure of a periodically performed motor action.
    1. Neuroscience

    Functional clustering of dendritic activity during decision-making

    Aaron Kerlin, Boaz Mohar ... Karel Svoboda
    In motor cortex pyramidal neurons, diverse task-related signals are distributed throughout the dendritic arbor and compartmentalized by dendritic distance and branching.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Self-capping of nucleoprotein filaments protects the Newcastle disease virus genome

    Xiyong Song, Hong Shan ... Zhi-Jie Liu
    Structural and functional studies reveal how Newcastle disease virus nucleocapsid protects its viral genome through a self-capping mechanism, which is important for new antiviral drug design.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Erasable labeling of neuronal activity using a reversible calcium marker

    Fern Sha, Ahmed S Abdelfattah ... Eric R Schreiter
    Protein engineering of a reversibly switchable fluorescent protein enables post-hoc reversible and repeatable marking of elevated calcium concentrations using blue light.
    1. Neuroscience

    Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion

    Timothy W Dunn, Yu Mu ... Misha B Ahrens
    Whole-brain activity imaging in larval zebrafish reveals brain regions that influence patterns of spontaneous movement to increase local exploration efficiency.
    1. Neuroscience

    Experience shapes activity dynamics and stimulus coding of VIP inhibitory cells

    Marina Garrett, Sahar Manavi ... Shawn R Olsen
    VIP inhibitory neurons are active in response to novel images but are suppressed by familiar stimuli and show ramping activity when expected stimuli are omitted.
    1. Computational and Systems Biology
    2. Neuroscience

    Flexible control of representational dynamics in a disinhibition-based model of decision-making

    Bo Shen, Kenway Louie, Paul Glimcher
    Local disinhibition provides a biologically plausible mechanism for flexible top-down control of network states that integrates normalized value coding, winner-take-all choice, and persistent activity in a single circuit of decision-making.

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