3,413 results found
    1. Genetics and Genomics
    2. Plant Biology

    DNA methylation in Arabidopsis has a genetic basis and shows evidence of local adaptation

    Manu J Dubin, Pei Zhang ... Magnus Nordborg
    The adaptation of Arabidopsis plants to the local environment is linked to DNA methylation.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Viruses are a dominant driver of protein adaptation in mammals

    David Enard, Le Cai ... Dmitri A Petrov
    Viruses drive adaptation at the scale of the whole proteome and not only in antiviral proteins in mammalian hosts.
    1. Genetics and Genomics

    The genetic basis for ecological adaptation of the Atlantic herring revealed by genome sequencing

    Alvaro Martinez Barrio, Sangeet Lamichhaney ... Leif Andersson
    Whole genome sequencing of 19 populations of Atlantic and Baltic herring reveals hundreds of individual loci underlying adaptation to a low salinity niche or timing of reproduction.
    1. Neuroscience

    Spike frequency adaptation supports network computations on temporally dispersed information

    Darjan Salaj, Anand Subramoney ... Wolfgang Maass
    Spike frequency adaptation provides spiking neural networks with long short-term memory.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The landscape of transcriptional and translational changes over 22 years of bacterial adaptation

    John S Favate, Shun Liang ... Premal Shah
    Parallel changes in organismal evolution can be observed even with disparate genomic changes due to similarity in functional outcomes, such as changes in molecular phenotypes like gene expression patterns.
    1. Microbiology and Infectious Disease

    Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation

    Mart M Lamers, Anna Z Mykytyn ... Bart L Haagmans
    Cell culture adaptation of SARS-CoV-2 is prevented on human airway cells with an active serine protease-mediated entry pathway, allowing the production of genetically stable virus stocks for laboratory experiments.
    1. Evolutionary Biology

    Repeatability of adaptation in sunflowers reveals that genomic regions harbouring inversions also drive adaptation in species lacking an inversion

    Shaghayegh Soudi, Mojtaba Jahani ... Sam Yeaman
    Adaptation to climate in sunflowers is highly polygenic, but still involves significant repeatability with many of the same genes being used by multiple species.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Rapid sex-specific adaptation to high temperature in Drosophila

    Sheng-Kai Hsu, Ana Marija Jakšić ... Christian Schlötterer
    Within 100 generations after an environmental shift in an evolution experiment, rapid sex-specific adaptation occurred, which is potentially facilitated by selection on standing variation in sex-specific genetic architecture.
    1. Computational and Systems Biology
    2. Chromosomes and Gene Expression

    Stochastic tuning of gene expression enables cellular adaptation in the absence of pre-existing regulatory circuitry

    Peter L Freddolino, Jamie Yang ... Saeed Tavazoie
    Stochastic tuning of gene expression could be a common mechanism through which eukaryotic cells adapt to challenging external environments, potentially including survival of infectious organisms within the host and adaptation of cancer cells to chemotherapy.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections

    Stefano G Giulieri, Romain Guérillot ... Benjamin P Howden
    A large-scale analysis of Staphylococcus aureus within-host evolution based on a comprehensive catalogue of bacterial genetic variation reveals an excess of genome degradation signatures in infecting strains and new genetic loci of clinically relevant adaptation.

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