38 results found
    1. Ecology
    2. Epidemiology and Global Health

    The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus

    Moritz UG Kraemer, Marianne E Sinka ... Simon I Hay
    The limits to the global distribution of the mosquitoes that transmit dengue and chikungunya have been predicted using a species distribution modelling approach.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Control of RNA viruses in mosquito cells through the acquisition of vDNA and endogenous viral elements

    Michel Tassetto, Mark Kunitomi ... Raul Andino
    Virus infection in mosquitoes initiates a highly discriminatory process in which fragments of viral RNA are reverse transcribed to create DNA copies that serve as templates of small antiviral RNAs.
    1. Microbiology and Infectious Disease

    An Aedes aegypti-associated fungus increases susceptibility to dengue virus by modulating gut trypsin activity

    Yesseinia I Angleró-Rodríguez, Octavio AC Talyuli ... George Dimopoulos
    Talaromyces (Tsp_PR) fungus render Aedes aegypti mosquitoes more susceptible to dengue virus infection through secreted molecules that impair midgut digestive enzyme transcription and activity.
    1. Epidemiology and Global Health

    The global burden of yellow fever

    Katy AM Gaythorpe, Arran Hamlet ... Neil Ferguson
    Yellow fever, a potentially deadly viral hemorrhagic fever, causes up to 82,000 deaths annually worldwide, and mass vaccination activities have reduced the burden by 47% in Africa.
    1. Epidemiology and Global Health

    Development of a confinable gene drive system in the human disease vector Aedes aegypti

    Ming Li, Ting Yang ... Omar S Akbari
    Highly efficient and confinable split gene drives are a new tool for the control of the dengue mosquito vector.
    1. Genetics and Genomics
    2. Neuroscience

    The ion channel ppk301 controls freshwater egg-laying in the mosquito Aedes aegypti

    Benjamin J Matthews, Meg A Younger, Leslie B Vosshall
    The ion channel ppk301 is required for the evaluation of water purity during egg-laying, which promotes offspring survival in the arboviral vector mosquito Aedes aegypti.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females

    Bretta Hixson, Xiao-Li Bing ... Nicolas Buchon
    RNAseq profiles of female Aedes body parts, gut regions, and blood-fed guts provide insight into the anatomical patterning of immune and digestive function, and demonstrate the sequential induction of multiple peptidase cohorts over the course of blood meal digestion.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mapping global environmental suitability for Zika virus

    Jane P Messina, Moritz UG Kraemer ... Simon I Hay
    A global map of environmental suitability for Zika virus and the estimated population living at potential risk can help refine public health guidelines, travel advisories and intervention strategies at a crucial time in the global emergence of this arbovirus.
    1. Epidemiology and Global Health

    Nationally-representative serostudy of dengue in Bangladesh allows generalizable disease burden estimates

    Henrik Salje, Kishor Kumar Paul ... Emily Gurley
    To maximize broad insight on disease burden, seroprevalence studies should be generalizable to the wider population, both in age and location.
    1. Neuroscience

    The cation channel TRPA1 tunes mosquito thermotaxis to host temperatures

    Román A Corfas, Leslie B Vosshall
    Female mosquitoes are exquisitely sensitive to human body heat, and the TRPA1 gene is required to focus their attraction toward thermal stimuli resembling warm-blooded hosts.

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