10 results found
    1. Cell Biology

    A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals

    Rosanna A Alegado, Laura W Brown ... Nicole King
    The development of colonies of cells in choanoflagellates, water-dwelling organisms that feed on bacteria, is triggered by the presence of very low concentrations of a lipid molecule produced by certain types of bacteria.
    1. Cell Biology

    Cell Biology: Molecular clue links bacteria to the origin of animals

    Michael G Hadfield
    Insight
    Formats available:
    • HTML
    • PDF
  1. A photograph of Rosanna Alegado in her lab. Image credit: Elyse Butler

    Talking Points: Rosanna Alegado on scientists and Indigenous communities

    Developing strong relationships between scientists and Indigenous communities is essential to promoting the rights of Indigenous Peoples and improving science.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Predicted glycosyltransferases promote development and prevent spurious cell clumping in the choanoflagellate S. rosetta

    Laura A Wetzel, Tera C Levin ... Nicole King
    A genetic screen reveals that two predicted glycosyltransferases promote rosette development and prevent cell clumping in one of the closest living relatives of animals, the choanoflagellate S. rosetta.
    1. Developmental Biology
    2. Genetics and Genomics

    The rosetteless gene controls development in the choanoflagellate S. rosetta

    Tera C Levin, Allison J Greaney ... Nicole King
    The establishment of forward genetics in S. rosetta reveals the first gene known to be required for choanoflagellate multicellular development.
    1. Cell Biology
    2. Evolutionary Biology

    Evolution of an ancient protein function involved in organized multicellularity in animals

    Douglas P Anderson, Dustin S Whitney ... Kenneth E Prehoda
    Experimentally reconstructing the evolution of the molecular complex that animals use to orient the mitotic spindle establishes a simple genetic and physical mechanism for the emergence of a function essential for multicellularity.
    1. Cell Biology
    2. Evolutionary Biology

    A flagellate-to-amoeboid switch in the closest living relatives of animals

    Thibaut Brunet, Marvin Albert ... Nicole King
    The closest living relatives of animals, the choanoflagellates, switch from a flagellate to an amoeboid phenotype under confinement.
    1. Developmental Biology
    2. Genetics and Genomics

    Genome editing enables reverse genetics of multicellular development in the choanoflagellate Salpingoeca rosetta

    David S Booth, Nicole King
    Genome editing in the choanoflagellate Salpingoeca rosetta opens newfound possibilities to functionally probe choanoflagellate genes that may illuminate the origin of their closest relatives, the animals.
    1. Evolutionary Biology

    Gene family innovation, conservation and loss on the animal stem lineage

    Daniel J Richter, Parinaz Fozouni ... Nicole King
    The genomes of animal progenitors evolved as mosaics of old, new, rearranged, and repurposed protein domains, genes and pathways and paved the way for the origin and evolution of animals.

Refine your results by:

Type
Research categories