133 results found
    1. Epidemiology and Global Health

    Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

    Ellen A Kearney, Paul A Agius ... Freya JI Fowkes
    A systematic review with multilevel modelling quantified the positive association between human antibodies to Anopheles salivary proteins with Anopheles-human biting rate and epidemiological measures of malaria transmission, highlighting their potential as a tool to measure vector exposure and malaria transmission.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Isolation and transcriptomic analysis of Anopheles gambiae oenocytes enables the delineation of hydrocarbon biosynthesis

    Linda Grigoraki, Xavier Grau-Bové ... Hilary Ranson
    Delineation of the cuticular hydrocarbon biosynthetic pathway in malaria vectors is a key step in understanding how mosquitoes adapt to anthropogenic change and vector control interventions.
    1. Microbiology and Infectious Disease

    Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

    Chiara Andolina, Wouter Graumans ... Teun Bousema
    The number of sporozoites expelled by mosquitoes that are infected with lab-cultured or naturally circulating Plasmodium falciparum gametocytes is heterogeneous and associated with the sporozoite load in their salivary glands.
    1. Developmental Biology

    Guy1, a Y-linked embryonic signal, regulates dosage compensation in Anopheles stephensi by increasing X gene expression

    Yumin Qi, Yang Wu ... Zhijian Jake Tu
    For the first time in a mosquito species an initial Y chromosome signal has been shown to regulate dosage compensation by increasing X chromosome gene expression.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High-resolution species assignment of Anopheles mosquitoes using k-mer distances on targeted sequences

    Marilou Boddé, Alex Makunin ... Mara KN Lawniczak
    Large-scale monitoring of Anopheles populations benefits from a robust and accurate species identification and plasmodium detection method that is applicable to the entire genus.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    GUY1 confers complete female lethality and is a strong candidate for a male-determining factor in Anopheles stephensi

    Frank Criscione, Yumin Qi, Zhijian Tu
    Evidence that the small GUY1 protein is a strong candidate for being a male-determining factor is provided via the establishment of Guy1 transgenic lines of mosquitoes that confer complete and stable female lethality.
    1. Ecology
    2. Genetics and Genomics

    Anopheles homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure

    Samuel E Champer, Isabel K Kim ... Jackson Champer
    Continuous space models indicate that current homing suppression drives may have difficulty eliminating wild mosquito populations, but building a successful drive may still be possible with current tools.
    1. Epidemiology and Global Health

    The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa

    Michelle M Riehle, Tullu Bukhari ... Kenneth D Vernick
    A common chromosome inversion in African malaria mosquito (Anopheles gambiae) is associated with differences in malaria infection, adult resting behavior and ecology, and may aid the most efficient vectors to evade malaria control.
    1. Epidemiology and Global Health

    Variation in natural exposure to anopheles mosquitoes and its effects on malaria transmission

    Wamdaogo M Guelbéogo, Bronner Pamplona Gonçalves ... Chris Drakeley
    Heterogeneity in exposure to malaria vectors, including sporozoite-infected mosquitoes, contributes to the variation in human infection risk and amplifies the local transmission potential.
    1. Microbiology and Infectious Disease

    Hemocyte differentiation to the megacyte lineage enhances mosquito immunity against Plasmodium

    Ana Beatriz F Barletta, Banhisikha Saha ... Carolina Barillas-Mury
    Toll signaling modulates hemocyte differentiation into the megacyte lineage and their recruitment to the midgut greatly enhances mosquito immunity against Plasmodium.

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