24 results found
    1. Neuroscience

    A spiral attractor network drives rhythmic locomotion

    Angela M Bruno, William N Frost, Mark D Humphries
    The neural population of the Aplysia's pedal ganglion are a low-dimensional spiral attractor, and the parameters of the attractor directly define the properties of the Aplysia's escape locomotion behaviour.
    1. Neuroscience

    Reinstatement of long-term memory following erasure of its behavioral and synaptic expression in Aplysia

    Shanping Chen, Diancai Cai ... David L Glanzman
    Storage of long-term memory in Aplysia does not require stable synapses.
    1. Neuroscience

    New learning while consolidating memory during sleep is actively blocked by a protein synthesis dependent process

    Roi Levy, David Levitan, Abraham J Susswein
    The brain inhibits the formation of new memories just after waking to safeguard the ongoing stabilization of existing memories during sleep.
    1. Neuroscience

    Role of protein synthesis and DNA methylation in the consolidation and maintenance of long-term memory in Aplysia

    Kaycey Pearce, Diancai Cai ... David L Glanzman
    Behavioral and synaptic investigations of long-term memory in Aplysia reveal differing roles for DNA methylation, protein synthesis during training and protein synthesis shortly after training with respect to memory consolidation and maintenance.
    1. Neuroscience

    Organelle calcium-derived voltage oscillations in pacemaker neurons drive the motor program for food-seeking behavior in Aplysia

    Alexis Bédécarrats, Laura Puygrenier ... Romuald Nargeot
    An atypical neuronal pacemaker mechanism triggers feeding motor pattern in Aplysia..
    1. Structural Biology and Molecular Biophysics

    Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor

    Pablo Miranda, Miguel Holmgren, Teresa Giraldez
    Allosteric modulation of BK channels, vital for the physiology of nerve, muscle and endocrine cells, is determined by direct coupling between gating ring RCK1 domains and the voltage sensor function.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory

    Claire C Chen, Joseph Han ... Andrej Luptak
    The mammalian CPEB3 self-cleaving ribozyme modulates expression of the CPEB3 mRNA and protein, altering translation of plasticity-related proteins and hippocampus-dependent memory.
    1. Neuroscience

    Luqin-like RYamide peptides regulate food-evoked responses in C. elegans

    Hayao Ohno, Morikatsu Yoshida ... Yuichi Iino
    Identification and functional characterization of C. elegans luqin-like arginine-tyrosine-NH2 (RYamide) peptides reveal their critical role in feeding-related processes.
    1. Developmental Biology
    2. Neuroscience
    Pond snail illustration

    The Natural History of Model Organisms: The unlimited potential of the great pond snail, Lymnaea stagnalis

    István Fodor, Ahmed AA Hussein ... Zsolt Pirger
    The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.
    1. Evolutionary Biology

    Microbial eukaryotes have adapted to hypoxia by horizontal acquisitions of a gene involved in rhodoquinone biosynthesis

    Courtney W Stairs, Laura Eme ... Andrew J Roger
    A number of microbial eukaryotes have adapted to low oxygen conditions by acquiring a gene that allows their mitochondrial electron transport chain to continue to function when oxygen is scarce.

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