11,800 results found
    1. Neuroscience

    Nucleus accumbens dopamine tracks aversive stimulus duration and prediction but not value or prediction error

    Jessica N Goedhoop, Bastijn JG van den Boom ... Ingo Willuhn
    The extracellular concentration of dopamine in the nucleus accumbens core is progressively diminished by white noise, an underutilized, easy-to-titrate aversive stimulus, but is unaffected by white-noise intensity, context valence, and associated probabilistic contingencies.
    1. Neuroscience

    Hippocampal place cell remapping occurs with memory storage of aversive experiences

    Garrett J Blair, Changliang Guo ... Hugh T Blair
    Imaging of neurons within the hippocampus, a memory region of the brain, reveals how the brain updates memories during different learning conditions compared to when learning is blocked by amnestic drugs.
    1. Neuroscience

    Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior

    Salvatore Lecca, Frank Julius Meye ... Manuel Mameli
    Glutamatergic signaling from the lateral hypothalamus instructs lateral habenular neurons for encoding aversive external stimuli to subsequently guide escape behaviours.
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    1. Neuroscience

    Chronic pain induces generalized enhancement of aversion

    Qiaosheng Zhang, Toby Manders ... Jing Wang
    Chronic pain distorts intensity coding in the anterior cingulate cortex to give rise to generalized anatomically nonspecific enhancement in pain aversion.
    1. Neuroscience

    Prolonged nicotine exposure reduces aversion to the drug in mice by altering nicotinic transmission in the interpeduncular nucleus

    Sarah Mondoloni, Claire Nguyen ... Alexandre Mourot
    Inter-individual variabilities in nicotine aversion are linked with responses of the interpeduncular nucleus to the drug.
    1. Neuroscience

    Midbrain dopamine neurons signal aversion in a reward-context-dependent manner

    Hideyuki Matsumoto, Ju Tian ... Mitsuko Watabe-Uchida
    Dopamine neurons signal value prediction errors (VPEs) integrating information about both reward and aversion, in low reward contexts, whereas VPEs in some dopamine neurons are distorted in high reward contexts.
    1. Neuroscience

    Fixation-pattern similarity analysis reveals adaptive changes in face-viewing strategies following aversive learning

    Lea Kampermann, Niklas Wilming ... Selim Onat
    A novel approach based on eye-movement patterns reveals adaptive changes during viewing of faces and fear generalization.
    1. Neuroscience

    Attenuated dopamine signaling after aversive learning is restored by ketamine to rescue escape actions

    Mingzheng Wu, Samuel Minkowicz ... Yevgenia Kozorovitskiy
    Interconnected ventral tegmental area and medial prefrontal cortex circuits causally link dopamine dynamics, aversive learning, and the effects of a promising rapidly acting antidepressant ketamine.
    1. Neuroscience

    Enteroendocrine cell types that drive food reward and aversion

    Ling Bai, Nilla Sivakumar ... Zachary A Knight
    A method for the genetic manipulation of enteroendocrine cells reveals how different intestinal cell types control food intake and drive post-ingestive learning.
    1. Evolutionary Biology

    Repeatability of adaptation in sunflowers reveals that genomic regions harbouring inversions also drive adaptation in species lacking an inversion

    Shaghayegh Soudi, Mojtaba Jahani ... Sam Yeaman
    Adaptation to climate in sunflowers is highly polygenic, but still involves significant repeatability with many of the same genes being used by multiple species.

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