1,362 results found
    1. Neuroscience

    Bayesian analysis of retinotopic maps

    Noah C Benson, Jonathan Winawer
    A novel Bayesian method of modeling retinotopic maps is more accurate than traditional voxel-wise methods and can be used to automatically derive high-quality maps.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    A Bayesian analysis of the association between Leukotriene A4 Hydrolase genotype and survival in tuberculous meningitis

    Laura Whitworth, Jacob Coxon ... Lalita Ramakrishnan
    In this ideal example of pharmacogenomics, individuals with a common variant in a gene encoding for an inflammatory lipid mediator benefit selectively from standard-of-care anti-inflammatory treatment used for tuberculous meningitis.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Bayesian machine learning analysis of single-molecule fluorescence colocalization images

    Yerdos A Ordabayev, Larry J Friedman ... Douglas L Theobald
    A physics-based, statistically rigorous mathematical model enables automated, objective interpretation of images from single-molecule fluorescence colocalization microscopy experiments.
    1. Neuroscience

    Bayesian analysis of phase data in EEG and MEG

    Sydney Dimmock, Cian O'Donnell, Conor Houghton
    A Bayesian model of phase angles illustrates a novel approach to the analysis of phase coherence in frequency-tagged experiments.
    1. Epidemiology and Global Health

    Efficacy profile of the CYD-TDV dengue vaccine revealed by Bayesian survival analysis of individual-level phase III data

    Daniel J Laydon, Ilaria Dorigatti ... Neil M Ferguson
    Bayesian survival analysis reveals comprehensive efficacy profile and mechanism of action for Sanofi-Pasteur’s CYD-TDV dengue vaccine, whereby vaccination acts as a silent, disease-free infection enhancing disease risk in seronegatives, but giving greater immunity in seropositives than two natural infections.
    1. Structural Biology and Molecular Biophysics

    Identification of electroporation sites in the complex lipid organization of the plasma membrane

    Lea Rems, Xinru Tang ... Lucie Delemotte
    Advanced data analysis of molecular dynamics simulations of complex lipid membranes provides a quantitative and predictive model of the molecular features that control electroporation.
    1. Neuroscience

    Control of entropy in neural models of environmental state

    Timothy H Muller, Rogier B Mars ... Jill X O'Reilly
    Evidence for neuromodulatory control of flexibility in human neural models.
    1. Neuroscience

    Bayesian inference of population prevalence

    Robin AA Ince, Angus T Paton ... Philippe G Schyns
    Bayesian estimation of the proportion of the population that would show an effect in an experiment provides a broadly applicable alternative to standard null hypothesis tests on the population mean with several advantages.
    1. Cancer Biology
    2. Computational and Systems Biology

    Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference

    Andrew R Lynch, Nicholas L Arp ... Mark E Burkard
    Chromosomal instability of cancer can be quantitatively measured by phylogenetic analysis of 200 tumor cells while using evolutionary principles to account for cellular selection.
    1. Neuroscience

    Neural activity tracking identity and confidence in social information

    Nadescha Trudel, Patricia L Lockwood ... Marco K Wittmann
    People's confidence in information and their neural correlates in key regions of the social brain are more stable when tracking social advice compared to non-social information.

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