17,453 results found
    1. Neuroscience

    Modified viral-genetic mapping reveals local and global connectivity relationships of ventral tegmental area dopamine cells

    Kevin Beier
    A modified viral strategy reveals that ventral tegmental area dopamine cells receive substantial inputs from local sources, including distributed GABAergic and serotonergic inputs from the midbrain as well as extensive inputs from other midbrain dopamine cells.
    1. Ecology
    2. Evolutionary Biology

    Seminal fluid compromises visual perception in honeybee queens reducing their survival during additional mating flights

    Joanito Liberti, Julia Görner ... Boris Baer
    After insemination, honeybee queens experience a rapid reduction in vision and flight performance, consistent with an ongoing sexual conflict over the number of mating flights that queens embark on.
    1. Neuroscience

    Social selectivity and social motivation in voles

    Annaliese K Beery, Sarah A Lopez ... Natalie S Bourdon
    Prairie and meadow voles show striking sex and species differences in social motivation to access conspecifics of different types (familiar versus unfamiliar and same-sex versus opposite-sex).
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    An analog to digital converter controls bistable transfer competence development of a widespread bacterial integrative and conjugative element

    Nicolas Carraro, Xavier Richard ... Jan Roelof van der Meer
    A new multistep hierarchical cascade controls activation of an integrative and conjugative element in a small subpopulation of cells in its bacterial host, yielding proficient DNA transferring cells.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Extensive transmission of microbes along the gastrointestinal tract

    Thomas SB Schmidt, Matthew R Hayward ... Peer Bork
    Microbial populations are continuous along the gastrointestinal tract, with increased transmission in colorectal cancer and rheumatoid arthritis patients.
  1. Meta-Research: A 10-year follow-up study of sex inclusion in the biological sciences

    Nicole C Woitowich, Annaliese Beery, Teresa Woodruff
    Sex-inclusive research practices have increased in many biological disciplines over the past decade, yet critical sex-based analyses and reporting have remained stagnant in most of these disciplines.
    1. Cell Biology
    2. Neuroscience

    Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

    Peer-Hendrik Kuhn, Alessio Vittorio Colombo ... Stefan F Lichtenthaler
    The metalloprotease ADAM10 modulates axon and synapse function by cleaving numerous synaptic and axonal membrane proteins in the central nervous system.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Resistome diversity in cattle and the environment decreases during beef production

    Noelle R Noyes, Xiang Yang ... Keith E Belk
    Interventions in feedlots and abattoirs place selective pressure on the beef cattle resistome, which differentially impacts the public health risk of antimicrobial resistance from beef production sources.
    1. Neuroscience

    Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity

    Eitan S Kaplan, Sam F Cooke ... Mark F Bear
    Parvalbumin-containing inhibitory neurons are crucial for expression of plasticity in adult visual cortex that supports visual recognition memory, but not for expression of ocular dominance plasticity that results from monocular deprivation.
    1. Chromosomes and Gene Expression

    A whole lifespan mouse multi-tissue DNA methylation clock

    Margarita V Meer, Dmitriy I Podolskiy ... Vadim N Gladyshev
    A robust mouse multi-tissue age predictor is presented that can be used to assess the DNA methylation age of mouse tissues and test the effects of longevity interventions.

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