2,226 results found
    1. Plant Biology

    Calcium specificity signaling mechanisms in abscisic acid signal transduction in Arabidopsis guard cells

    Benjamin Brandt, Shintaro Munemasa ... Julian I Schroeder
    The calcium-dependent signaling pathway during ABA-dependent stomatal closure requires the calcium-independent pathway, and calcium signaling specificity is mediated by PP2C protein phosphatases.
    1. Neuroscience

    Microglial calcium signaling is attuned to neuronal activity in awake mice

    Anthony D Umpierre, Lauren L Bystrom ... Long-Jun Wu
    Microglial processes engage calcium signaling in response to hyper- or hypo-active shifts in neuronal activity.
    1. Neuroscience

    Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium

    Stephanie C Gantz, Brooks G Robinson ... Kim A Neve
    The loss of calcium-dependent D2 autoreceptor desensitization caused by prior in vivo cocaine exposure may be conferred by an unexpected role of the D2L splice variant as an autoreceptor.
    1. Cell Biology

    Ion channels and calcium signaling in motile cilia

    Julia F Doerner, Markus Delling, David E Clapham
    Direct patch clamp of ependymal motile cilia reveals that voltage-gated calcium channels in the cell body dominate their electrical and calcium signaling properties.
    1. Microbiology and Infectious Disease

    Calcium signaling through a transient receptor channel is important for Toxoplasma gondii growth

    Karla Marie Márquez-Nogueras, Miryam Andrea Hortua Triana ... Silvia NJ Moreno
    A transient receptor channel in Toxoplasma gondii that conducts calcium represents the first molecular element that initiates upstream calcium signals that activate parasite pathogenic pathways.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calcium signaling

    Naser Nasrollahzadeh, Peyman Karami ... Dominique P Pioletti
    The loading-induced temperature evolution phenomenon in the knee joint modulates chondrogenic cells response to loading and accordingly opens a new paradigm that is coined 'thermo-mechanobiology'.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Calcium and bicarbonate signaling pathways have pivotal, resonating roles in matching ATP production to demand

    Maura Greiser, Mariusz Karbowski ... Liron Boyman
    A novel signaling system in heart mitochondria in which the byproduct of energy metabolism, CO2/bicarbonate, acts as the primary signal to tune mitochondrial ATP production while keeping energy supply in tight synchronization with energy consumption.
    1. Neuroscience

    Distinct signatures of calcium activity in brain mural cells

    Chaim Glück, Kim David Ferrari ... Bruno Weber
    Increases of extracellular potassium silence capillary pericyte calcium signaling, suggesting a participation of capillary pericytes in the potassium-mediated neurovascular communication.
    1. Immunology and Inflammation
    2. Cell Biology

    Calcium-mediated shaping of naive CD4 T-cell phenotype and function

    Vincent Guichard, Nelly Bonilla ... Cédric Auffray
    Calcium-calcineurin signaling cascade drives the acquisition of both the phenotype of the most self-reactive naive CD4 T cells and their enhanced cell-intrinsic ability to commit into induced regulatory T cells upon activation.
    1. Developmental Biology

    Endothelial Ca2+ oscillations reflect VEGFR signaling-regulated angiogenic capacity in vivo

    Yasuhiro Yokota, Hiroyuki Nakajima ... Naoki Mochizuki
    Visualization and quantitative analyses of calcium ion oscillations in the endothelial cells of zebrafish embryos reveal how vascular endothelial growth factor (VEGF) and Dll4/Notch signaling regulate sprouting angiogenesis.

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