Alba Timón-Gómez, Alexandra L Scharr ... Andy J Chang
An atypical configuration of mitochondrial electron transport chain proteins may underlie the exquisite sensitivity of the carotid body to small decreases in oxygen availability.
David Macias, Andrew S Cowburn ... Randall S Johnson
Genetic and physiological analyses demonstrate the essential role of the transcription factor HIF-2alpha in the sympathetic nervous system control of the ventilatory response to hypoxia.
Embryonic fate-mapping approaches in zebrafish, Xenopus and lamprey illuminate the evolutionary origins of carotid body glomus cells and pulmonary neuroendocrine cells.
Ibrahim T Mughrabi, Jordan Hickman ... Stavros Zanos
Long-term, dose-controlled vagus nerve stimulation (VNS) is feasible in mice using a multi-lab validated implantation procedure, allowing therapeutic testing of VNS in many disease models.
Mitchell Bishop, Maximilian Weinhold ... Shahriar SheikhBahaei
The introduced Python tool was used to characterize breathing behaviors of common marmosets in room air and acute hypoxic (10% O2) and hypercapnic (6% CO2) conditions.
Amit Frishberg, Inge van den Munckhof ... Irit Gat-Viks
A novel type of metabolic syndrome, derived from computational modeling of phenotypic diversity in normal physiological settings, increases the risk of certain complex diseases.
Stunning new scan data of an enigmatic fish from the Early Devonian of Australia, Ligulalepis, is identified as a stem osteichthyan, specifically, as the sister taxon to the 'psarolepids' plus crown osteichthyans.
Andrew S Cowburn, David Macias ... Randall S Johnson
Radiotelemetric and genetic studies of peripheral tissue response show that a peripheral tissue can dynamically alter cardiovascular adaptation to changes in environmental oxygen.