Differential physical interactions between bacteria in mixed microcolonies trigger cell sorting.

Novel modelling strategies can integrate the dynamics of processes regulating the intestinal epithelium at multiple scales in homeostasis and following perturbations to provide unprecedented insights into the biology of the epithelium and support the development of safer novel drug candidates.

A genetic mapping study in more than 1000 yeast individuals reveals the complexity of trans-acting genetic influences on transcriptome variation in unprecedented depth and detail.

Using self-organization, cells can collectively leverage defects in nematic and hexatic orders to localize mechanical stresses and remove an unwanted cell with their preferred path to achieve this explored here by independently tuning cell–cell and cell–substrate adhesion strengths.

The role of amyloid-β-aggregation sequence and of the various domains in the physiological function of the FLO11-encoded adhesin in the yeast Saccharomyces cerevisiae are disclosed in this report.

Cells utilize a membrane-mediated mechanism for mechanosensation, which involves the disruption of lipid rafts and a signal relayed to an ion channel.

Pre-complexation of vinculin with talin’s R8 domain facilitates nascent adhesion maturation by unfolding talin, increasing vinculin binding, and thereby transmitting traction forces to the environment.

Epithelial tissue remodeling during Drosophila embryonic development is quantitatively described by a simple law relating myosin activity and cell flow.

Spontaneous elongation of epithelial colonies is related to the orientation of the mean nematic cell elongation field, as shown and tested with experiments and theory.

The C-terminus of A_2A receptor drives oligomer formation via an intricate network of disulfide bonds, hydrogen bonds, electrostatic interactions, and hydrophobic interactions, all of which are enhanced by depletion interactions.