Chronic exposure to a potent chemical contact sensitizer drives a self-limiting expansion of a polyclonal population of T cells recognizing a small number of dominant antigens.

Mineralized placental tissue from Late Byzantine Troy enables the detailed reconstruction of genomes of mixed bacterial species responsible for maternal sepsis in the ancient world.

Structural and biochemical analysis of a protein called Ecp6, which is produced by a tomato fungus, reveals how the protein prevents plants from launching an immune response to the chitin in fungal cell walls.

Shark's T cells suggest plasticity in diversification mechanisms used by vertebrate lymphocytes, including somatic hypermutation in the thymus.

Introduction of single photoswitchable unnatural amino acid into a neuronal receptor provides reversible, rapid and robust control of its activity by light, representing an important contribution to the fast expanding field of optopharmacology.

Single-cell transcriptomic profiling and systematic analysis of pulmonary neuroendocrine cells identifies over 40 hormones and neuropeptides expressed in myriad combinations, and predicts their targets in mouse and human lung, revealing extraordinary sensory and signaling diversity and potential physiological functions.

The chitin-triggered immune response is mediated by a LYK5 and CERK1 receptor complex in Arabidopsis.

The principle underlying the appearance of the growth plate, an organ responsible for longitudinal growth, has implications for various cartilage pathologies including growth abnormalities in children, trauma and osteoarthritis.

4-sulfation at the non-reducing end of chondroitin sulfate glycosaminoglycan chains is essential for inhibition of axonal growth.

The muscle circadian clock regulates RNA-binding motif 20 (Rbm20) gene expression, providing a novel mechanism for titin splicing and isoform expression with implications for muscle structure and function.