Perception is proposed to be a dynamic motor-sensory closed-loop process in which information flows through the environment and the brain in continuous loops, converging towards steady-state percepts.
Hannah L Payne, Jennifer L Raymond, Mark S Goldman
A comprehensive modeling approach reconciles experimental observations with classic plasticity mechanisms in the cerebellar cortex, demonstrating how learning-related changes in neural activity can appear to contradict the sign of the underlying plasticity when feedback is present.
Elizabeth Nicholson, Dmitry A Kuzmin ... Dimitri Michael Kullmann
Neurons can synchronize, supporting flexible communication among brain areas; closed-loop optogenetics allows the frequency and power of population oscillations to be dissociated, providing a tool to interrogate how networks couple.
A brain–computer interface for real-time identification of transient neural activity patterns enables causal inference of the role of these patterns in cognition through closed-loop manipulation.
Mary K Thompson, Maria F Rojas-Duran ... Wendy V Gilbert
Asc1/RACK1 promotes the translation of mRNAs associated with the translational closed loop complex, which have short open reading frames and encode proteins required for core metabolic processes.
Patrick D Ganzer, Michael J Darrow ... Robert L Rennaker II
Precisely-timed bursts of closed-loop vagus nerve stimulation during rehabilitation restore neural connectivity and substantially improve recovery of motor function after SCI.
Jean-Paul Noel, Edoardo Balzani ... Dora E Angelaki
Primates use their eyes to keep track of spatial goals, and this strategy is reflected by the functional connectivity between a traditionally considered optic flow area (dorsomedial superior temporal area) and prefrontal cortex.
Hippocampal sharp-wave ripples are not required for rats to successfully perform spatial tasks that rely on memorization of locations at short timescales.
José-Maria Moreira, Pavel M Itskov ... Carlos Ribeiro
The optoPAD system combines real-time behavioral analysis with optogenetic manipulations to study how animals adapt to dynamic gustatory environments and to identify the circuit basis of feeding.