Chick optic fissure closure is a powerful new model system for epithelial fusion and has revealed Netrin-1 as a conserved and essential mediator of tissue fusion in multiple contexts.
Andrius Pašukonis, Shirley Jennifer Serrano-Rojas ... Lauren A O'Connell
Extensive field studies in poison frogs reveal that sex and species differences in parental behavior drive differences in space use patterns but not navigational performance and highlight the interplay between androgen levels and poison frog spatial behavior.
Aurora Alvarez-Buylla, Marie-Therese Fischer ... Lauren A O'Connell
Alkaloid-binding globulin (ABG) is a novel protein discovered in the plasma of poison frogs that transports many alkaloids, with structural homology to mammalian hormone carriers and amphibian biliverdin-binding serpin.
Stephan Heermann, Lucas Schütz ... Joachim Wittbrodt
The lens-averted domains of the optic vesicle are reservoirs of neuroretinal cells that flow into the developing optic cup in a process that is critically influenced by BMP signaling.
Phenotypic evolution can originate from variations in very precocious developmental events, starting even before fecundation, during the fabrication of the egg in the mother's gonad.
Hironobu Okuno, Francois Renault Mihara ... Hideyuki Okano
Neural crest cells differentiated from patient-derived cells with mutations in the chromatin remodeler CHD7 show defective delamination, migration and motility in vitro, and defective migration in chick embryos.
Céline Portal, Panteleimos Rompolas ... Carlo Iomini
Primary cilia of neural crest-derived cells mediate Indian hedgehog-induced signal transduction in the periocular mesenchyme and are required for normal anterior segment development.