Gaining genetic control over neural modules that drive the grooming of each Drosophila body part reveals how mechanisms for selecting among competing behavioral choices are used to generate sequences of actions.
Stefanie Hampel, Claire E McKellar ... Andrew M Seeds
A grooming sequence is produced by a neural architecture that readies different movements simultaneously, and a mechanism where prioritized suppression between the movements determines their sequential performance.
The growth environment driven ratio of ATP to growth rate, called absolute growth, determines the final population composition of Staphylococcus aureus and Pseudomonas aeruginosa when in co-culture.
Michele LeRoux, Robin L Kirkpatrick ... Joseph D Mougous
The death of bacterial kin cells releases a danger signal that activates a posttranscriptional response in surviving cells, resulting in the rapid elaboration of interbacterial competition factors.
The engagement of DNA crossings is shown to license ATP hydrolysis and DNA cleavage by topoisomerase VI, a finding with mechanistic ramifications for related GHKL ATPases and meiotic recombination machineries.
The production of two secondary metabolites is co-regulated in a bacterium via an intermediate in one pathway that is converted into signals to activate the second pathway.
Swati Gaikwad, Fardin Ghobakhlou ... Alan G Hinnebusch
A mutant impaired for ribosome recycling exhibits translational reprogramming wherein strong mRNAs outcompete weak mRNAs, also observed when preinitiation complexes are diminished by eIF2α phosphorylation or 40S ribosomal subunit depletion.
The hepatic endocannabinoid/CB1R system controls the soluble leptin receptor’s expression and/or subsequent release by Trib3-induced regulation of C/EBP homologous protein levels in hepatocytes to affect leptin signaling in the liver.
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