840 results found
    1. Neuroscience

    Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

    Yu Huang, Anli A Liu ... Lucas C Parra
    Direct in-vivo measurements in the human brain test validity of detailed computational models of trancranial electric stimulation and show that electric fields in the brain are weaker than currently assumed.
    1. Neuroscience

    Neuromodulation: Transcranial electric stimulation seen from within the brain

    Angel V Peterchev
    Computer models can make transcranial electric stimulation a better tool for research and therapy.
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    1. Computational and Systems Biology
    2. Neuroscience

    Biophysical models reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis

    Kira M Düsterwald, Christopher B Currin ... Joseph V Raimondo
    Mathematical models with experimental validation show that chloride transporters in the cell membrane, and not negatively charged impermeant molecules, generate the driving force used by GABA receptors to silence neurons.
    1. Computational and Systems Biology
    2. Ecology

    Emergent regulation of ant foraging frequency through a computationally inexpensive forager movement rule

    Lior Baltiansky, Guy Frankel, Ofer Feinerman
    Rather than complex decisions, it is the motion of individuals that allows for collective foraging regulation in ant colonies.
    1. Computational and Systems Biology
    2. Medicine

    A computational model predicts sex-specific responses to calcium channel blockers in mammalian mesenteric vascular smooth muscle

    Gonzalo Hernandez-Hernandez, Samantha C O'Dwyer ... Colleen E Clancy
    A computer model predicts different mechanisms of blood pressure regulation and effective hypertensive therapy for males and females, thereby serving as a foundational tool for improved treatment precision.
    1. Physics of Living Systems

    Hydrodynamic model of fish orientation in a channel flow

    Maurizio Porfiri, Peng Zhang, Sean D Peterson
    A hydrodynamic model of fish swimming in a channel predicts a critical flow speed for fish to successfully swim against a flow, unveiling a passive mechanism for rheotaxis to emerge without access to any sensory information.
    1. Cell Biology

    Specific targeting of inflammatory osteoclastogenesis by the probiotic yeast S. boulardii CNCM I-745 reduces bone loss in osteoporosis

    Maria-Bernadette Madel, Julia Halper ... Claudine Blin-Wakkach
    Transcriptomic comparison of inflammatory and steady-state osteoclasts reveals differences in their ability to sense their environment, which makes it possible to selectively inhibit inflammatory osteoclastogenesis and reduce bone loss in osteoporosis.
    1. Neuroscience

    Brian 2, an intuitive and efficient neural simulator

    Marcel Stimberg, Romain Brette, Dan FM Goodman
    Brian 2 is a software package for neural simulations that makes it both easy and computationally efficient to define original models for computational experiment.
    1. Neuroscience

    Dopamine enhances model-free credit assignment through boosting of retrospective model-based inference

    Lorenz Deserno, Rani Moran ... Raymond J Dolan
    Cooperation between model-free and model-based control systems is boosted by enhancing dopamine levels.
    1. Neuroscience

    Therapeutic effects of anodal transcranial direct current stimulation in a rat model of ADHD

    Da Hee Jung, Sung Min Ahn ... Byung Tae Choi
    High-definition anodal transcranial stimulation alleviated cognitive deficits, affected dopaminergic neurotransmission factors, increased expression of several neurotrophic factors involving brain-derived neurotrophic factor (BDNF), and activated hippocampal neurogenesis.

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