The development of neural responses proceeds through both the expansion and contraction of receptive field structure, and in addition depends upon changes in excitability of individual cells.
Developmental hearing loss causes perceptual deficits that are best explained by degraded auditory cortical encoding that is recorded during task performance.
The development of complex motion processing in higher-level visual cortex involves functional changes in primary visual cortex, indicating coordinated development in multiple nodes of the visual hierarchy.
Mid-gestational exposure to maternal immune activation drives a sequence of transcriptional signatures and developmental pathology in embryonic mouse cortex, culminating in altered lamination and cellular lineage specification.
Eleonora Franzoni, Sam A Booker ... F Gregory Wulczyn
The regulation of Phf6 by miR-128 is a developmental timing mechanism that influences cortical lamination, neuronal morphology and intrinsic excitability.
Kerstin Hasenpusch-Theil, Christine Laclef ... Thomas Theil
Primary-cilia-mediated processing of the Gli3 transcription factor enables the formation of subtypes of projection neurons in appropriate numbers during the development of the cerebral cortex.
Embryonic PI3K-Yap activity regulates apical adhesion and proliferation of neural progenitors lining the lateral ventricular surface, to maintain the smooth, non-folded mouse brain and to prevent developmental hydrocephalus.