Microbial cells optimally structure their proteomes in order to mutually maximize metabolism and translation, as established by an extensive comparison between data and a low-dimensional model of cellular physiology.

There was substantial change in primary care activity following the onset of the COVID-19 pandemic in March 2019 as indicated by key measures reflective of clinical activity in general practice but service was largely restored by April 2021.

Computational modeling and a cell cycle-reporting axolotl reveal how spinal cord regeneration can be achieved by a signal that propagates 828 μm from the injury site during the first 85 hours post-amputation.

The growth of wild Drosophila larvae on fruits is promoted by a yeast releasing essential nutrients extracellularly or by a stable association with a nutrient-providing bacterium established by microbe–microbe interactions.

Systematic quantification of abdominal organ health parameters using deep learning generates new insights into the genetic architecture of cardiometabolic health traits.

Responses to a survey reveal how core facilities could improve and encourage good research practices.

C. elegans equalizes the expression of X-chromosome genes between the sexes by reducing the recruitment of RNA polymerase II to promoters of X-linked genes in hermaphrodites, using a chromosome-restructuring complex called condensin.

A single protein catalyzes site-specific DNA recombination upon blue-light illumination.

Genetically restoring Mecp2 expression only in GABAergic neurons in a mouse model of Rett syndrome improves inhibitory signaling, extends lifespan and rescues most but not all behavioral deficits.

An extensive interface between the proteins RBBP4 and MTA1 defines the three-dimensional architecture of the core NuRD complex and determines the recruitment of the complex to chromatin.