eLife is introducing a new article type—called Tools and Resources—to highlight new experimental techniques, datasets, software tools and other resources.
Christopher P Mancuso, Hyunseok Lee ... Ahmad S Khalil
Laboratory experiments using a microbial community and mathematical modeling reveal how environmental disturbances can predictably alter the diversity and composition of an ecosystem.
A curated resource to study the brain RNA expression patterns of the genes that regulate palmitoylation is presented, alongside a detailed exploration of how these patterns can inform future research.
A new multi camera imaging platform simultaneously captures large-area, high-resolution video of unconstrained small model organisms and provides behavioral measurements that span multiple spatial scales.
Geoffrey W Meissner, Aljoscha Nern ... FlyLight Project Team
Single neuron images of Drosophila driver lines reveal neuron shape and are searchable, enabling comparisons to electron microscopy and prediction of intersectional neuron targeting strategies.
A cargo recognition α-helix was identified in Nup358, which is required for activation of a dynein-dependent transport pathway that is essential for brain development.
Evolutionary trade-offs enhance efficacy of antibiotic therapy by constraining bacterial adaptation in dependence of drug order and trade-off effect size.
The highly metabolically active hair cells of the zebrafish lateral line have a distinct mitochondrial phenotype consisting of small mitochondria apically and large, networked mitochondrion basally, demonstrating a nonuniform mitochondrial architecture that is sculpted by cellular activity.
Valentina Baldazzi, Delphine Ropers ... Hidde de Jong
A coarse-grained model of microbial growth coupling fluxes of carbon and energy shows that resource allocation is a major explanatory factor of the observed variability of growth rates and growth yields across different bacterial strains.