A series of quantitative behavioural and opto-physiological analyses using a novel robot microscope system reveals that C. elegans computes the time-differential and time-integral of sensory information for decision-making during olfactory navigation.

Older adults show reduced adaptation of decision-making strategies to dynamically changing situational demands.

Dopamine attenuates exploration during decision-making via a reduction of neural tracking of uncertainty.

Human behaviour in a continuous decision making task adapts to the overall statistics of the sensory environment, and these adaptations are also reflected in changes in neural responses to incoming sensory evidence.

Local disinhibition provides a biologically plausible mechanism for flexible top-down control of network states that integrates normalized value coding, winner-take-all choice, and persistent activity in a single circuit of decision-making.

Macaque monkeys play Pac-Man with strategy-based hierarchical decision-making, a cognitive capacity hitherto unknown in them.

Divisive normalisation effects on decision making caused by distractor options can be reduced by stimulating the parietal cortex using transcranial magnetic stimulation.

Intraoperative human brain recordings during a memory task reveal that when participants inhibit memory formation, the subthalamic nucleus shows higher beta power and beta coherence with areas of the lateral cortex implicated in memory processing.

Ketamine, an NMDA receptor antagonist and experimental model for schizophrenia, produces decision-making deficits in monkeys, which are predicted by a lowering of cortical excitation-inhibition balance in a spiking circuit model.

Speeded value-based decisions between two options can be affected by a third, high-value distractor that captures attention and slows down the choice process.