Combining CRISPR/Cas9 genome editing with gene drives may enable scientists to reversibly edit the genomes of diverse wild populations, an advance that could help eliminate diseases, support sustainable agriculture, and control invasive species.

Increasing the intra-species phenotypic diversity of a plant-beneficial bacterium effectively improves probiotic consortium functioning and plant growth promotion in agricultural systems.

Artificial selection on communities drives the evolution of interactions and establishes community-level inheritance.

Recurrent neural network models enable prediction and design of health-relevant metabolite dynamics in synthetic human gut communities.

Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.

Analytical and numerical analyses reveal that the number of coexisting species exceeds the number of resource only for the structurally unstable case of linear tradeoff.

Genome engineering and phenotyping in vivo reveal surprising new features of adaptive amino acid substitutions that were previously inaccessible.

If released in the wild, current CRISPR-based gene drive systems designed to alter populations could spread much farther than intended, despite the evolution of drive resistance.

Life is constrained in its sampling of protein sequence space to catalyze one of the most energetically challenging biochemical reactions.

Continuous space models indicate that current homing suppression drives may have difficulty eliminating wild mosquito populations, but building a successful drive may still be possible with current tools.