A phase-based analysis reveals wave-like spatiotemporal organization of the human sleep spindle, a brain oscillation critical to sleep-dependent memory consolidation, and elucidates its role in coordinating activity of neural networks distributed across the cortex.

Dnajb6 is identified as a novel sick sinus syndrome causative gene that exhibits a unique expression pattern within a subpopulation of sinus node pacemaker cells.

Inhibition of RyR2 hyperactivity with dantrolene not only prevents VT/VF and SCD but also heart failure by mitigating calcium dysfunction in pressure-overloaded hearts.

A computer model of human cardiomyocyte was produced and validated on independent datasets, overcoming shortcomings of its predecessors, also yielding broadly relevant insights and results on major ionic currents.

Infants' vocalisations are contingent on their own stress physiology, and alter the inter-personal dynamics of how stress states are shared across the infant-caregiver dyad.

Pronounced cerebellar activation during unexpected omission of a potentially harmful event suggests that the cerebellum has to be added to the neural network processing prediction errors underlying emotional associative learning.

Why is the alligator heart so similar to the hearts of birds and mammals?

Personalized heart muscle cells made from stem cells in the laboratory could be used to check an individual’s response to potential new drugs before clinical trials.

Functional imaging (fMRI) across four mammalian species maps the brain areas engaging in burst-suppression activity during anesthesia, and uncovers differences between primates and rodents.

A genetically diverse panel of subject-specific induced pluripotent stem cells models the in vitro susceptibility of cardiac cells to develop a cardiotoxic drug response.