961 results found
    1. Ecology
    2. Chromosomes and Gene Expression

    Emerging Technology: Concerning RNA-guided gene drives for the alteration of wild populations

    Kevin M Esvelt, Andrea L Smidler ... George M Church
    Combining CRISPR/Cas9 genome editing with gene drives may enable scientists to reversibly edit the genomes of diverse wild populations, an advance that could help eliminate diseases, support sustainable agriculture, and control invasive species.
    1. Ecology
    2. Epidemiology and Global Health

    Predictors of human-infective RNA virus discovery in the United States, China, and Africa, an ecological study

    Feifei Zhang, Margo Chase-Topping ... Mark EJ Woolhouse
    In three different regions including the United States, China, and Africa, virus discoveries were strongly associated with GDP and land use, but were less likely to be associated with climate and biodiversity variables than at a global scale.
    1. Ecology

    Point of View: A transatlantic perspective on 20 emerging issues in biological engineering

    Bonnie C Wintle, Christian R Boehm ... William J Sutherland
    Horizon scanning has been used to identify opportunities and risks presented by 20 emerging issues in the field of biological engineering.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Microfluidic-based mini-metagenomics enables discovery of novel microbial lineages from complex environmental samples

    Feiqiao Brian Yu, Paul C Blainey ... Stephen R Quake
    Microfluidic-based mini-metagenomics enables the investigation of environmental microbial communities in high-throughput and with single-cell resolution, facilitating genome binning and quantification of function, abundance, and genome variation.
    1. Neuroscience

    Impact of inner ear malformation and cochlear nerve deficiency on the development of auditory-language network in children with profound sensorineural hearing loss

    Yaoxuan Wang, Mengda Jiang ... Hao Wu
    Innovative MRI mapping of the auditory pathway reveals that peripheral auditory structure significantly impacts the development of the central auditory-language network in children with profound sensorineural hearing loss, emphasizing the need for early speech input and tailored interventions.
    1. Cell Biology
    2. Neuroscience

    Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

    Heather L Smith, Jennifer N Bourne ... Kristen M Harris
    Three-dimensional electron microscopy (3DEM) demonstrates the dependence on presynaptic mitochondria for vesicle mobilization as dendritic spines are silently added at P15 or synapses are silently enlarged in adults after long-term potentiation.
    1. Cell Biology

    Development of a versatile high-throughput mutagenesis assay with multiplexed short-read NGS using DNA-barcoded supF shuttle vector library amplified in E. coli

    Hidehiko Kawai, Ren Iwata ... Hiroyuki Kamiya
    A sophisticated classical mutagenesis assay with next-generation sequencing technology presents a benefit to future research on mutagenesis, DNA repair, and cancer.
    1. Microbiology and Infectious Disease

    Multimeric single-domain antibody complexes protect against bunyavirus infections

    Paul J Wichgers Schreur, Sandra van de Water ... Jeroen Kortekaas
    Llama-derived single-domain antibodies, formatted as bispecific antibodies with human Fc domains, reduce and prevent bunyavirus-induced morbidity and mortality in mice upon prophylactic and therapeutic administration.
    1. Evolutionary Biology

    An armoured marine reptile from the Early Triassic of South China and its phylogenetic and evolutionary implications

    Andrzej S Wolniewicz, Yuefeng Shen ... Jun Liu
    A new fossil sheds light on the evolution of an aquatic lifestyle in extinct reptiles and supports a close phylogenetic relationship between archosaurs (crocodiles, dinosaurs, birds, and kin) and turtles.
  1. Open-source technology in publishing: Community call, June 28

    The recording of June’s community call on open source technology for publishing is now available.

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