The conductance-based encoding model creates a new bridge between statistical models and biophysical models of neurons, and infers visually-evoked excitatory and inhibitory synaptic conductances from spike trains in macaque retina.
Thomas Ridler, Jonathan Witton ... Jonathan T Brown
Dementia-related tau pathology reduces speed encoding in the medial entorhinal cortex and is associated with reduced grid cell function, whilst head direction tuning remains intact.
Laurent Jutras-Dubé, Ezzat El-Sherif, Paul François
Propagation, speed and shapes of genetic waves of expression during development can be modeled by a simple interplay between two transcriptional modules (dynamic/static), which explains robustness and precision of patterning.
Christina M Merrick, Tanner C Dixon ... Richard B Ivry
An electrode-wise encoding model based on physiological recordings from the cortical surface revealed a striking hemispheric asymmetry where the encoding of ipsilateral movement was stronger in the left hemisphere compared to the right hemisphere.
Jamie D Costabile, Kaarthik A Balakrishnan ... Martin Haesemeyer
Model identification of neural encoding is an accessible system for the analysis of neural data that allows identifying and characterizing arbitrary relationships between neural activity and task-related variables such as behavior, stimuli, or internal states.
Computational and theoretical analyses offer novel and unexpected insight into how complex, naturally occurring odor mixtures are parsed and normalized at the very first stage of olfaction.
Daniel B Dorman, Joanna Jędrzejewska-Szmek, Kim T Blackwell
Inhibition enhances the spatial specificity of high calcium influx for cooperatively stimulated synapses, suggesting that inhibitory inputs may regulate both synapse-specific and heterosynaptic plasticity to support learning and memory.
The direction-selective circuit in the retina adjusts the contributions of excitatory and inhibitory mechanisms under different stimulus conditions to generate context-dependent neural representations of visual features.
Multi-electrode recordings and modeling are combined to reveal the transformations of signals from cones to bipolar cells and then to ganglion cells within the primate retina.
