Morphological and functional rejuvenation upon exit from adult reproductive diapause in C. elegans is independent of germline signaling, but instead involves somatic nucleolar activation and expansion of the RNA pool.

Fluctuations of a transcription factor that coincide with the G2 phase of the cell cycle pattern two interspersed cell fates in a multicellular system.

By inactivating DA1, DAR1 and DAR2 through deubiquitination, UBP12 and UBP13 regulate leaf growth, cell area and endoreduplication.

The SP1/KLF transcription factor Huckebein controls endoreplication in the Drosophila salivary gland, ensuring proper morphogenesis during organ formation.

Mitosis of reduplicated chromosomes is under careful regulation and can be perfectly executed.

Crosses of loaches with various genetic and karyptype divergence cause different reproductive outcomes in hybrids, ranging from sexual reproduction to sterility, inviability, and clonality among females.

Ploidy-increasing endocycles may represent a tradeoff between loss of regenerative capacity and preservation of tissue architecture.

Terminally differentiated neurons and glia can re-enter the cell cycle to become polyploid in the adult fly brain, to protect cells from DNA damage-associated death.

Discovery of a novel mode of sexual reproduction, termed pseudosexual reproduction, in fungi where both parents are required for mating but only one contributes to the meiotic progeny, similar to hybridogenesis in animals.