Genome-wide profiling of R-loops at near single-nucleotide resolution reveals distinct R-loop boundaries depending on the presence and location of the first exon-intron junction.

A gene duplication event has permitted the functional specialization of a homeodomain transcription factor through changes in exon-intron organization and these changes have supported the evolution of a major, phylum-level morphological novelty.

During evolutionary progression of Alu-exons, repressive U-tracts buffer sudden gains in 3' splice site strength and prevent inclusion of cryptic exons.

New methods reveal that complex local splicing variations are more prevalent in animals than previously appreciated, and demonstrate that local splicing variations are relevant for studies of development, gene regulation and neurodegenerative diseases.

Comprehensive analysis of alternative splicing from human droplet-based scRNA-seq data identifies genes with regulated splicing conserved in mouse and mouse lemur.

The transition to the aggregative stage of Capsaspora owczarzaki, a close unicellular relative to Metazoa, is associated with significant upregulation of orthologs of genes that are important for multicellularity in metazoans.

Horizontal gene transfer (HGT) analysis in polyextremophile red algae (Cyanidiales) provides explanations for the nonexistence of cumulative effects and eukaryotic pangenomes, and highlights differences between HGT and native genes.

Interconnected RNA processing mechanisms ensure the fidelity of non-conventional mRNA splicing during the unfolded protein response.

Discovery of a novel neuropeptide signalling system in a deuterostome invertebrate reveals the evolutionary origin of prolactin-releasing peptide and its relationship with neuropeptides in protostome invertebrates.

A transcription factor that regulates skeleton formation in sea urchin embryos has evolved a new domain that is essential for this process.