Histone deacetylase 1 (Hdac1) plays a crucial role in maintaining differential histone acetylation states of enhancers in various germ layers and regulates the transcriptional program both temporally and spatially.

The nuclear pore complex is transiently proteolyzed during cell differentiation and the nuclear proteome experience dramatic change.

Structural and biochemical studies of Kap123 revealed the mechanisms by which Kap123 recognizes H3- and H4-NLSs through two lysine-binding pockets and by which evolutionarily conserved diacetylation of H4-NLS facilitates Kap123-H3-NLS mediated nuclear translocation.

The pioneering endocytic protein FCHo2 promotes clathrin-coated structures assembly via the formation of phosphoinositide-enriched domains at the boundary of cargo receptors.

Endocytosis is triggered by membrane-associated proteins that transform the clathrin adaptor into an active complex.

Retrotransposon-derived messenger RNA plays a critical role in rice root development via sequestration of miR171, which suggests a novel trans-acting regulation by transposable elements.

TRACC (Transcriptional Readout Activated by Cell-cell Contacts) is an engineered molecular tool that detects and records cell-cell contacts in mammalian systems.

Odor conditioning induces two changes in olfactory neurons: non-associative sensory adaptation to odor history, and associative, bidirectional changes in behavioral output that are oppositely regulated in aversive and appetitive learning.

The muniscin protein FCHO1 interacts with, and activates, the adapter protein-2 complex (AP-2) to promote the assembly of clathrin-coated vesicles.

Echolocating toothed whales can detect and react to sudden prey movements during close approaches with speeds similar to ultra-fast tracking responses in human vision.