98 results found
    1. Evolutionary Biology

    Preservation of three-dimensional anatomy in phosphatized fossil arthropods enriches evolutionary inference

    Achim H Schwermann, Tomy dos Santos Rolo ... Thomas van de Kamp
    X-ray imaging reveals well-preserved internal characters in mineralized arthropods from the Paleogene, urging the reexamination of previously neglected fossil collections.
    1. Neuroscience

    DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation

    Laura Morcom, Timothy J Edwards ... Linda J Richards
    Incomplete interhemispheric fissure remodelling determines corpus callosum size in humans and BTBR N2 mice that carry a deletion in Draxin.
    1. Developmental Biology

    Detailed analysis of chick optic fissure closure reveals Netrin-1 as an essential mediator of epithelial fusion

    Holly Hardy, James GD Prendergast ... Joe Rainger
    Chick optic fissure closure is a powerful new model system for epithelial fusion and has revealed Netrin-1 as a conserved and essential mediator of tissue fusion in multiple contexts.
    1. Neuroscience

    Enhancement of encoding and retrieval functions through theta phase-specific manipulation of hippocampus

    Joshua H Siegle, Matthew A Wilson
    The ability of mice to encode new memories or retrieve existing ones can be selectively manipulated by using optogenetics to inhibit hippocampal activity at specific phases of the theta cycle.
    1. Developmental Biology
    2. Neuroscience

    Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

    Stephan Heermann, Lucas Schütz ... Joachim Wittbrodt
    The lens-averted domains of the optic vesicle are reservoirs of neuroretinal cells that flow into the developing optic cup in a process that is critically influenced by BMP signaling.
    1. Developmental Biology
    2. Neuroscience

    Mechanisms underlying microglial colonization of developing neural retina in zebrafish

    Nishtha Ranawat, Ichiro Masai
    Genetic and imaging analysis reveal that microglial precursors use ocular blood vessels as a pathway to enter the optic cup and subsequently infiltrate the retina preferentially through the neurogenic region.
    1. Cell Biology
    2. Neuroscience

    TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons

    Emily Bowie, Sarah C Goetz
    Signaling at the primary cilium is important to sustain the morphology, connectivity, and survival of a key neural population within the brain.
    1. Neuroscience

    Human hippocampal responses to network intracranial stimulation vary with theta phase

    Sarah M Lurie, James E Kragel ... Joel L Voss
    Human hippocampal connectivity to network afferents varies continuously with the phase of the local theta oscillation, confirming a putative mechanism by which neural oscillations modulate human hippocampal function.
    1. Developmental Biology
    2. Neuroscience

    DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

    Laura Morcom, Ilan Gobius ... Linda J Richards
    Axon guidance molecules DCC and NTN1 regulate astroglial-mediated interhemispheric remodelling required for corpus callosum formation in humans and mice.
    1. Neuroscience

    Resting-state gamma-band power alterations in schizophrenia reveal E/I-balance abnormalities across illness-stages

    Tineke Grent-'t-Jong, Joachim Gross ... Peter J Uhlhaas
    Resting-state MEG-activity and MRS-GABA/Glx measurements reveal that there is a significant shift in excitability during the course of schizophrenia, involving hyperexcitability during the onset and a reduction at chronic stages.

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