2,499 results found
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Full spectrum flow cytometry reveals mesenchymal heterogeneity in first trimester placentae and phenotypic convergence in culture, providing insight into the origins of placental mesenchymal stromal cells

    Anna Leabourn Boss, Tanvi Damani ... Anna ES Brooks
    Full spectrum flow cytometry reveals a high degree of placental mesenchymal cell heterogeneity, which is lost with culture, highlighting the importance of detailed ex vivo phenotyping to optimise the use of these cells in downstream applications.
    1. Cell Biology

    Viscoelastic properties of suspended cells measured with shear flow deformation cytometry

    Richard Gerum, Elham Mirzahossein ... Ben Fabry
    Under fluid shear, living cells deform elliptically, align in flow direction, and rotate, from which their frequency-dependent viscoelastic properties can be inferred.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data

    James W Opzoomer, Jessica A Timms ... Shahram Kordasti
    ImmunoCluster permits nonspecialist users to interrogate liquid and imaging mass, and flow cytometry datasets, resolving novel layers of cellular heterogeneity and insight, as well as producing publishable outputs and figures.
    1. Computational and Systems Biology

    Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models

    Morteza Chalabi Hajkarim, Ella Karjalainen ... Kyoung-Jae Won
    compaRe can be used to optimize cytometric high-parameter immunophenotypic characterization of heterogeneous cell populations.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A precisely adjustable, variation-suppressed eukaryotic transcriptional controller to enable genetic discovery

    Asli Azizoglu, Roger Brent, Fabian Rudolf
    A new gene expression tool enables precise control of protein dosage over a large range and paves the way for new genetic discoveries.
    1. Cell Biology
    2. Immunology and Inflammation

    Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception

    Stefanie Gryzik, Yen Hoang ... Ria Baumgrass
    A novel binning approach provides evidence for super-functional T cells with high activation potential and which exhibit Tfh-like functionalities and can help B cells.
    1. Cell Biology
    2. Immunology and Inflammation

    In silico-labeled ghost cytometry

    Masashi Ugawa, Yoko Kawamura ... Sadao Ota
    Stain-free ‘imaging’ flow cytometry enables high-throughput cell classification and sorting based on machine-predicted labels.
    1. Stem Cells and Regenerative Medicine

    Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues

    Andrew W DeVilbiss, Zhiyu Zhao ... Sean J Morrison
    A method was developed for the metabolomic analysis of small numbers of flow cytometrically isolated cells from rare cell populations such as hematopoietic stem cells and circulating cancer cells.
    1. Immunology and Inflammation

    High-dimensional analysis of intestinal immune cells during helminth infection

    Laura Ferrer-Font, Palak Mehta ... Johannes U Mayer
    A systematic optimization of intestinal digestion protocols allows for the isolation and high-dimensional flow cytometric analysis of intestinal immune cells during murine helminth infection.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    A critical region of A20 unveiled by missense TNFAIP3 variations that lead to autoinflammation

    Elma El Khouri, Farah Diab ... Irina Giurgea
    Enhanced proteasomal degradation of TNFAIP3 proteins carrying missense variations is one of the pathophysiological mechanisms underlying HA20.

Refine your results by:

Type
Research categories