6 results found
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals

    William E Diehl, Nirali Patel ... Welkin E Johnson
    Endogenous virus sequences in the genomes of modern mammals reveal the global spread of an ancient virus lineage, including frequent interspecies transmission, adaptation, and emergence spanning several million years of mammalian evolution
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Co-option of an endogenous retrovirus envelope for host defense in hominid ancestors

    Daniel Blanco-Melo, Robert J Gifford, Paul D Bieniasz
    The reconstitution of a functional envelope protein from an extinct hominid retrovirus reveals its receptor and an ancient host defense that may have led to the extinction of the virus.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Virology: Pushing the envelope

    Julia H Wildschutte, John M Coffin
    Primates have co-opted a viral gene to produce an envelope protein that prevents infection by the HERV-T virus and likely contributed to the extinction of this virus.
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  1. Paper with 1000 citations and barcode-like frequency of citations in IMRAD sections

    Investigating the context of citations

    A report from a short project using natural language processing and machine learning on open-access content to understand what lies beneath a citation.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Angiomotin functions in HIV-1 assembly and budding

    Gaelle Mercenne, Steven L Alam ... Wesley I Sundquist
    Angiomotin (AMOT) is a cellular host factor that links HIV-1 to the ubiquitin E3 ligase, NEDD4L, and promotes virion assembly and envelopment.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    HIV-1 uncoating by release of viral cDNA from capsid-like structures in the nucleus of infected cells

    Thorsten G Müller, Vojtech Zila ... Hans-Georg Kräusslich
    HIV-1 capsids enter the host cell nucleus, where they are partially disrupted to release the viral genome upon completion of reverse transcription.

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